Synopsis of recent research by authors named "Martyna Sochacka"
- Martyna Sochacka's recent research focuses on the mechanisms of fibroblast growth factors (FGFs) and their receptors (FGFRs) in cancer biology, particularly in overcoming drug resistance in cancer cells and understanding unconventional secretion pathways of FGF homologous factors (FHFs).
- Significant findings include the development of strategies to target the FGF1/FGFR1 axis using compounds like honokiol and FGF ligand traps, revealing new avenues for combating cancer drug resistance.
- Sochacka's work also highlights that FGF12, historically considered non-signaling, has been shown to have important extracellular roles and contributes to anti-apoptotic responses and ribosome biogenesis, thus redefining the functions attributed to FHFs in cell signaling.
