Pergolide mesylate administration does not decrease blood thyroid hormone concentrations and thyroid function in horses.

Objective: Pergolide, labeled for the treatment of pituitary pars intermedia dysfunction, is 90% protein bound and might cause a decrease in blood thyroid hormone concentrations by displacing them from binding proteins. This study investigated the effect of pergolide on the equine thyroid function.

Methods: This was an analytic, observational, cohort study.