Publications by authors named "Marton K A Cavalcante"
Article Synopsis
- Visceral leishmaniasis (VL) is a serious public health issue caused by protozoa and can be fatal if not treated, with current treatment options facing challenges like toxicity and drug resistance.
- Novel derivatives of 1,2,4-oxadiazole have shown potential as new drug candidates, demonstrating high oral absorption and good bioavailability.
- One particular derivative displayed strong selectivity against the parasite forms involved in VL, causing significant cell damage and decreasing mitochondrial function, indicating its effectiveness as a treatment option.
