Publications by authors named "Martinus Stander"
Background: This study aims at evaluating the cost-effectiveness of a 2-dose schedule human papillomavirus (HPV) vaccination programme of HPV and human immunodeficiency virus (HIV) naïve 12-year-old girls, in addition to cervical cancer (CC) screening alone, in South Africa. The study aims to account for both the impact of the vaccine among girls who are HIV-positive (HIV+) as well as HIV-negative (HIV-) population.
Methods: A previously published Markov cohort model was adapted to assess the impact and cost-effectiveness of a HPV vaccination programme in girls aged 12 years (N = 527 900) using the AS04-adjuvanted HPV-16/18 vaccine from a public payer perspective.
Article Synopsis
- Potent antiretroviral therapy significantly lowers viral loads in HIV-positive individuals, improving their health and enabling their immune systems to recover.
- The concept of using early treatment as a means to prevent the spread of HIV, known as treatment as prevention (TasP), has potential but faces numerous practical challenges that must be addressed for it to be effective.
- Conducting community randomized controlled trials and operational studies is crucial to gather evidence, inform public health policies, and evaluate the real-world applicability of early HIV treatment strategies.