Impact of Hospital-based Multidisciplinary Anticoagulation Stewardship Programs.

Antithrombotic therapies, especially anticoagulants, are high-risk medications with increased potential for adverse events. The development and implementation of a well-functioning, designated, multidisciplinary anticoagulation stewardship program (MASP), tailored to each hospital-center's needs, has the primary objectives of improving patient-centered outcomes, minimizing undesirable anticoagulation-related adverse events and minimizing hospital length of stay (LOS) and other patient-related costs. Such stewardship programs are pivotal in supporting busy clinicians with consultation on challenging clinical case scenarios, ensuring appropriate use of valuable healthcare resources, achieving compliance with anticoagulant-associated accreditation standards, and positively impacting patient-specific morbidity/mortality outcomes.

[Venous thromboembolism risk and prophylaxis in the acute hospital care setting (ENDORSE II study): results of a Mexican national cross-sectional study].

Background: It is well known that a significant proportion of hospitalized medical and surgical patients with risk factors for deep vein thrombosis (DVT) are not receiving thromboprophylaxis. We designed this study to evaluate the proportion of at-risk patients and the proportion of those receiving recommended prophylaxis.

Methods: We conducted a multicentric cross-sectional survey that included medical and surgical patients from 43 hospitals throughout Mexico.

Predictive value of digital subtraction angiography in patients with tuberculous meningitis.

Digital subtraction angiography (DSA) was performed in 24 adults with tuberculous meningitis (TBM) and results were correlated with 24 admission and 16 follow-up CT examinations. 19 MRI studies and clinical outcome at a mean follow-up of 44 weeks. DSA was abnormal in 11 patients.

[In vitro comparison of ciprofloxacin with other antibiotics against multiresistant gram-negative bacilli].

In 2784 specimens submitted to the Clinical Microbiology Laboratory of the Instituto Nacional de Neurología from May 1989 to January 1990, 140 (5.0%) had gram negative bacilli (GNB) resistant to five or more antibiotics. One hundred different isolates recovered from urine, tracheal aspirates, blood, cerebrospinal fluid, surgical wound infections and other sites were studied.