Publications by authors named "Martine Claveau"
Article Synopsis
- The study aimed to investigate the relationship between different management strategies for patent ductus arteriosus (PDA) and neurodevelopmental impairment (NDI) in extremely preterm infants at 18-24 months.
- Researchers conducted a retrospective analysis of infants born before 29 weeks from two units that employed distinct PDA treatment approaches: one aggressive and the other conservative.
- Results showed similar rates of NDI across both groups, indicating that the management strategies for PDA did not significantly affect neurodevelopmental outcomes in these infants.
Article Synopsis
- The study aimed to create a head ultrasound (HUS) screening protocol for infants born before 32 weeks gestational age in order to accurately identify severe brain injuries while using fewer resources.
- A retrospective analysis was conducted on infants in a neonatal intensive care unit (NICU) from 2011 to 2017, identifying key risk factors for severe brain injury and evaluating the effectiveness of HUS at different times during their hospital stay.
- The results indicated that by using a risk-based screening approach, the number of head ultrasounds performed could be reduced by 40% while still effectively detecting severe brain injuries, improving efficiency in neonatal care.
Article Synopsis
- The study aimed to evaluate the occurrence and risk factors for autism spectrum disorder (ASD) in preterm infants born before 29 weeks of gestational age.
- Researchers conducted a retrospective cohort study involving 300 infants, finding a combined ASD incidence of 15.7% and identifying significant risk factors such as male sex, being small for gestational age, older maternal age, and maternal smoking during pregnancy.
- The findings highlight the need for ASD evaluations in infants born prematurely and suggest ongoing monitoring of developmental outcomes beyond 18 months of corrected age.
Background: Hypertensive disorders of pregnancy (HDP) are associated with dysfunctional placentation and are a major cause of maternal and neonatal morbidity and mortality. Twin pregnancies have a larger placental mass and are a risk factor for HDP. The effect of HDP on neonatal outcomes in twin pregnancies is unknown.
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- Umbilical cord blood gas values can indicate the acid-base balance of newborns and may relate to worse outcomes in preterm infants, specifically those born before 29 weeks of gestation.
- This study analyzed data from extremely preterm neonates (23 to 28 weeks gestation) to explore the connection between umbilical cord blood gas values and mortality, as well as severe neurological injuries.
- Key findings revealed that low arterial pH (≤7.1) and base excess (≤-12 mmol/L) were linked to over a 2.5-fold increase in the likelihood of poor neonatal outcomes, including death and severe brain injuries.
Article Synopsis
- The study aimed to evaluate the effects of a nonintervention policy on death and bronchopulmonary dysplasia (BPD) rates in premature infants compared to standard treatment.
- Researchers analyzed 1249 infants from two sites: one continued traditional medical treatments while the other adopted a nonintervention approach starting in late 2013.
- Results showed no change in outcomes for infants born at 26-29 weeks gestation, but there was a significant 31% increase in death/BPD rates among infants born before 26 weeks in the nonintervention site.
Objective: To investigate the association between fluid and sodium status in the first 10 postnatal days and death/bronchopulmonary dysplasia (BPD) among infants born <29 weeks' gestation.
Study Design: Single center retrospective cohort study (2015-2018) of infants born 23-28 weeks'. Three exposure variables were evaluated over the first 10 postnatal days: cumulative fluid balance (CFB), median serum sodium concentration, and maximum percentage weight loss.
Objective: The study aimed to assess the association of tracheal intubation (TI) and where it is performed, and the number of TI attempts with death and/or severe neurological injury (SNI) among preterm infants.
Study Design: Retrospective cohort study of infants born 23 to 32 weeks, admitted to a single level-3 neonatal intensive care unit (NICU) between 2015 and 2018. Exposures were location of TI (delivery room [DR] vs.
Importance: Episodes of severe airway obstruction (SAO) are reported during surfactant administration.
Objective: To evaluate adherence to and impact of a surfactant protocol on adverse events.
Methods: An evidence-based protocol for surfactant administration was developed (2011), implemented (2012) and re-implemented (2014), including three major steps: lung recruitment, manual bagging, and bolus instillation.
Objective: To provide comprehensive, contemporary information on the actuarial survival of infants born at 22-25 weeks of gestation in Canada.
Study Design: In a retrospective cohort study, we included data from preterm infants of 22-25 weeks of gestation admitted to neonatal intensive care units participating in the Canadian Neonatal Network between 2010 and 2017. Infants with major congenital anomalies were excluded.
Background: The current resuscitation guidelines for neonates recommend considering stopping resuscitation efforts if the heart rate remains undetectable after 10 min of adequate resuscitation. However, this recommendation does not take into account the gestational age (GA) of the neonates. We determined the outcomes of neonates with a 10-min Apgar score of zero (Apgar = 0) with respect to their GA.
View Article and Find Full Text PDFObjective: This study aimed to determine the association of caloric intake, protein intake, and enteral feed initiation time in the first 3 days of life with weight loss percentage (%WL) at 7 days among infants born 32 to 34 weeks' gestational age (GA).
Study Design: This is a retrospective cohort study of 252 infants admitted to a neonatal intensive care unit. Patient data included patient characteristics, daily weight, intake, and method of nutrition in the first 3 days.
Trends in sex-specific differences in outcomes in extreme preterms: progress or natural barriers?
Arch Dis Child Fetal Neonatal Ed
March 2020
Objective: To examine the differences and trends of outcomes of preterm boys and girls born at <29 weeks' gestation.
Design: A retrospective cohort study.
Setting: Data collected by the Canadian Neonatal Network.
Bronchopulmonary dysplasia (BPD) is a common long-term complication in premature newborns requiring ventilatory support and is the most common cause of chronic diffuse lung disease in this population. We present the clinical course of a premature newborn with a complicated neonatal respiratory course that was initially thought to be related to BPD, but it did not respond to the typical therapies for this condition. Due to the findings of periventricular nodular heterotopia, the diagnosis of a filamin A gene mutation was eventually made, which explained the respiratory pathology of this patient.
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