Impact of hypomanic personality traits on brain functional connectivity during a dynamic theory-of-mind task.

Hypomanic personality traits are present in the general population and represent a risk factor for developing bipolar disorder. This personality style, notably its social component, is linked to difficulties in theory of mind (i.e.

Activation of the left medial temporal gyrus and adjacent brain areas during affective theory of mind processing correlates with trait schizotypy in a nonclinical population.

Schizophrenia, a severe psychiatric disorder, is associated with abnormal brain activation during theory of mind (ToM) processing. Researchers recently suggested that there is a continuum running from subclinical schizotypal personality traits to fully expressed schizophrenia symptoms. Nevertheless, it remains unclear whether schizotypal personality traits in a nonclinical population are associated with atypical brain activation during ToM tasks.

Neurosyphilis with dementia and bilateral hippocampal atrophy on brain magnetic resonance imaging.

Background: This article reports a rare case of active neurosyphilis in a man with mild to moderate dementia and marked hippocampal atrophy, mimicking early onset Alzheimer's disease. Few cases have so far described bilateral hippocampal atrophy mimicking Alzheimer's disease in neurosyphilis.

Case Presentation: The patient presented here is a 33 year old Bulgarian male, whose clinical features include progressive cognitive decline and behavioral changes over the last 18 months.

Cognitive dysfunction profile and arterial stiffness in type 2 diabetes.

Background: The causative mechanisms of type 2 diabetes (T2D) on cognitive dysfunction are still undergoing development.

Aim: To explore the cognitive dysfunction profile and its relation to the potential role of arterial stiffness in later middle age T2D patients.

Methods: We studied 37 patients with T2D (age range 45-65 years) and 22 normal controls.