Centella asiatica extract-SiO nanocomposite: More than a drug-delivery system for skin protection from oxidative damage.

An innovative nanotechnology-based approach was used for the preparation of Centella asiatica (C. asiatica) extract-SiO nanocomposites, specifically tailored for skin protection from oxidative damage. Different amounts of C.

Green Preparation of Antimicrobial 1D-Coordination Polymers: and by Ultrasonication of Zn(II) Salts and 4,4'-Bipyridine.

We report on the green preparation of one-dimensional metal coordination polymers by sonochemical approach. The spacer ligand 4,4'-bipyridine was ultrasonicated with chloride or acetate zinc salts to obtain and , respectively. Benign solvents such as ethanol and water were selected as reaction media, and the synthesis took place in a few minutes-a very short time compared to conventional methods where some days' synthesis is required.

High Energy Ball Milling and Liquid Crystal Template Method: A Successful Combination for the Preparation of Magnetic Nano-Platforms.

In this study, we present the preparation of superparamagnetic ordered mesoporous silica (SOMS) for biomedical applications by the combination of high energy ball milling (HEBM) and the liquid crystal template method (LCT) to produce a material comprised of room temperature superparamagnetic Fe₃O₄ nanoparticles in a MCM-41 like mesostructured silica. In a typical synthesis, a mixture of Fe₂O₃ and silica was sealed in a stainless-steel vial with steel balls. Ball milling experiments were performed in a vibratory mill apparatus.

Exploring the Effect of Iron Metal-Organic Framework Particles in Polylactic Acid Membranes for the Azeotropic Separation of Organic/Organic Mixtures by Pervaporation.

A microporous carboxylate metal-organic framework MIL-100 Fe was prepared as submicron particles by microwave-assisted hydrothermal synthesis (Fe-MOF-MW). This product was explored, for the first time, for the preparation of polylactic acid (PLA) mixed matrix membranes. The produced MOF was characterised by powder X-ray diffraction (PXRD), environmental scanning electron microscopy (ESEM) as well as by thermogravimetric analysis (TGA) and nitrogen adsorption/desorption.

Microemulsions: The of Ferrite Nanoparticle Synthesis.

Ferrite nanoparticles (NPs) are of special interest for a wide range of applications. Microemulsions represent the of ferrite NP preparation offering a series of advantages with respect to other methods due the possibility to confine reactions into nanosized reactors. They allow the preparation in mild synthesis conditions of a wide variety of nanostructured ferrites with controlled composition, particle size and shape.

Formation of metallic silver and copper in non-aqueous media by ultrasonic radiation.

Concentrated suspensions of silver and copper salts in silicone oil were heated to 200 °C and irradiated with ultrasonic energy for different time durations. Characterization of the products was done using X-ray powder diffraction. In most cases, metallic Ag or Cu were obtained, together with their oxide forms AgO and CuO.

Synthesis and thermodynamics of Ag-Cu nanoparticles.

Metallic silver, copper, and Ag-Cu nanoparticles (NPs) have been produced by a chemical reduction method. The obtained nanoparticles were characterized by powder X-ray diffraction (XRD) and transmission electron microscopy (TEM). A side-segregated configuration was observed for the one-pot synthesized Ag-Cu NPs, and the melting temperature depression of about 14 °C was found by differential scanning calorimetry (DSC).

Characterization and cytotoxicity studies on liposome-hydrophobic magnetite hybrid colloids.

The aim of this study was to highlight the main features of magnetoliposomes prepared by TLE, using hydrophobic magnetite, and stabilized with oleic acid, instead of using the usual hydrophilic magnetite surrounded by sodium citrate. These biocompatible magnetoliposomes (MLs) were prepared with the purpose of producing a magnetic carrier capable of loading either hydrophilic or lipophilic drugs. The effect of different liposome/magnetite weight ratios on the stability of magnetoliposomes was evaluated by monitoring the mean diameter of the particles, their polydispersity index, and zeta potential over time.

Drug silica nanocomposite: preparation, characterization and skin permeation studies.

The aim of this work was to evaluate silica nanocomposites as topical drug delivery systems for the model drug, caffeine. Preparation, characterization, and skin permeation properties of caffeine-silica nanocomposites are described. Caffeine was loaded into the nanocomposites by grinding the drug with mesoporous silica in a ball mill up to 10 h and the efficiency of the process was studied by XRPD.

PEGylation and preliminary biocompatibility evaluation of magnetite-silica nanocomposites obtained by high energy ball milling.

High energy ball milling (HEBM) has been used for the first time to prepare PEGylated magnetite-silica (Fe(3)O(4)-SiO(2)) nanocomposites intended to be used for biological purposes. Surface amine groups were introduced by a silanization reaction involving 3-aminopropyl triethoxysilane (APTS) followed by PEGylation to yield long-term stable and stealth nanocomposites of 200nm in diameter. The efficient coverage by PEG chains was shown by isothermal titration calorimetry (ITC) where PEGylated nanocomposites did not interact with BSA compared to non-PEGylated counterparts which led to a significant change in enthalpy.