Publications by authors named "Martina Miglietti"
Article Synopsis
- Parkinson's disease (PD) is a brain disorder that can cause problems with smell and digestion before the main symptoms appear.
- People with PD often have trouble smelling, swallowing, and digesting food.
- New research suggests that tiny germs in our gut and nose might help cause PD by affecting a protein in the brain called α-synuclein.
Labeling of macrophages with perfluorocarbon (PFC)-based compounds allows the visualization of inflammatory processes by F-magnetic resonance imaging (F-MRI), due to the absence of endogenous background. Even if PFC-labeling of monocytes/macrophages has been largely investigated and used, information is lacking about the impact of these agents over the polarization towards one of their cell subsets and on the best way to image them. In the present work, a PFC-based nanoemulsion was developed to monitor the course of inflammation in a model of spinal cord injury (SCI), a pathology in which the understanding of immunological events is of utmost importance to select the optimal therapeutic strategies.
View Article and Find Full Text PDF