Biologics in the treatment of calcium pyrophosphate deposition disease: a systematic literature review.

The main aim of this systematic literature review (SLR) was to summarise the evidence in the use of biological therapies in calcium pyrophosphate deposition disease (CPPD). We performed a SLR using PubMed, Embase and Cochrane databases. Only studies reporting the efficacy of biologics in CPPD were selected.

How normal is the enthesis by ultrasound in healthy subjects?

Objectives: To explore the prevalence of the ultrasound (US) findings of enthesitis in a group of healthy subjects.

Methods: US assessments of quadriceps, patellar and Achilles tendons, and plantar fascia entheses were performed by a rheumatologist on 82 healthy volunteers focusing on the US findings indicative of "active" inflammation according to the Outcome Measures in Rheumatology (OMERACT) definitions.

Results: Eight hundred and twenty entheses were evaluated in 82 healthy subjects.