Publications by authors named "Martina Brandlhuber"

Background: Postoperative ileus (POI) involves an intestinal inflammatory response that is modulated by afferent and efferent vagal activation. We aimed to identify the potential influence of the vagus nerve on POI by tracking central vagal activation and its role for peripheral inflammatory changes during the early hours after surgery.

Methods: C57BL6 mice were vagotomized (V) 3-4 days prior to experiments, while control animals received sham vagotomy (SV).

View Article and Find Full Text PDF
Article Synopsis
  • - The EOS imaging system provides low-radiation long-leg radiographic images without stitching issues and was evaluated for its accuracy in grading osteoarthritis (OA) compared to conventional radiographs.
  • - A study with 142 patients showed that EOS images align closely with the Kellgren and Lawrence (KL) scoring and OARSI systems for assessing OA, demonstrating excellent inter-rater reliability.
  • - While EOS images are reliable for OA grading and joint space measurement, some features like subchondral sclerosis may not be as clearly visible as in traditional radiographs.
View Article and Find Full Text PDF
Article Synopsis
  • The study evaluates the effectiveness of dynamic contrast-enhanced MRI (DCE-MRI) in detecting malignant infiltration of the mesorectal fascia (MRF) and lymph nodes in rectal cancer patients.
  • Compared to conventional MRI (cMRI), DCE-MRI significantly improved sensitivity and specificity for identifying small lymph node metastases and enhanced the detection of MRF infiltration.
  • Overall, DCE-MRI provides valuable additional diagnostic information for treatment planning in patients with locally advanced rectal cancer.
View Article and Find Full Text PDF

Purpose: It is controversial whether patients fare better with conservative or surgical treatment in certain stages of acute diverticulitis (AD), in particular when phlegmonous inflammation or covered micro- or macro-perforation are present. The aim of this study was to determine long-term quality of life (QoL) for AD patients who received either surgery or conservative treatment in different stages.

Methods: We included patients treated for AD at the University Hospital Grosshadern, Munich, Germany, between January 1, 2000, and December 31, 2010.

View Article and Find Full Text PDF

Objectives: To demonstrate the feasibility of fast Dual-Source CT (DSCT) and to evaluate the clinical utility in chest/abdomen/pelvis staging CT studies.

Methods: 45 cancer patients with two follow-up combined chest/abdomen/pelvis staging CT examinations (maximally ±10 kV difference in tube potential) were included. The first scan had to be performed with our standard protocol (fixed pitch 0.

View Article and Find Full Text PDF

Objectives: The purpose of our study was to evaluate the potential of x-ray propagation-based phase-contrast imaging (PCI) computed tomography (CT) for the detection and characterization of early changes after ischemia-reperfusion (IR) in a standardized rat liver transplantation (LTx) model.

Materials And Methods: Syngeneic orthotopic liver transplantation was performed in male Lewis rats. Ischemia-reperfusion injury (IRI)-induced changes of liver parenchyma were investigated in a time-dependent manner (2, 16, 24, and 32 hours).

View Article and Find Full Text PDF