Publications by authors named "Martin Vazan"
Background: This article summarizes the results of the German guideline on radiofrequency denervation of the facet joints and the sacroiliac joint. Evidence on the indications, test blocks and technical parameters are presented.
Objective: The aim is to avoid overtreatment and undertreatment, which is also of socioeconomic importance.
Study Design: Systematic review of the literature and subsequent meta-analysis for the development of a new guideline.
Objectives: This manuscript summarizes the recommendations from a new clinical guideline published by the German Spine Society. It covers the current evidence on recommendations regarding the indication, test blocks and use of radiofrequency denervation.
Sticky platelet syndrome (SPS) is a thrombophilia caused by the increased aggregability of platelets in response to the addition of low concentrations of epinephrine (EPI) and/or adenosine diphosphate (ADP). Some of the single nucleotide polymorphisms (SNP), alleles and haplotypes of platelet glycoprotein receptors were proved to have a role in the etiology of thrombotic episodes When comparing SPS and the control group, in VEGFA rs3025039, the p value for both CC vs. TT and CT vs.
View Article and Find Full Text PDFStudy Design: We performed a prospective nonblinded single center observational study.
Objective: To investigate the relationship between expectations, outcome, and satisfaction with the outcome in patients undergoing cervical spine stabilization surgery.
Summary Of Background Data: In modern healthcare, patient-reported outcome measures and patient satisfaction have become an important aspect of quality control.
Background: In patients with ankylosing spinal disease, including ankylosing spondylitis and diffuse idiopathic skeletal hyperostosis, even low-impact trauma can lead to complex injuries. The injuries seem to be highly unstable and associated with greater mortality rates compared with the general spine trauma population.
Methods: We reviewed the medical records of a consecutive series of 41 patients (34 men, 7 women) with ankylosing spinal disease and unstable traumatic spine injuries who were admitted to our department from 2007 to 2016.
Background: Minimally invasive spine surgery (MISS) has been increasingly advocated during the last decade with new studies being reported every year. Minimally invasive spine procedures, such as minimally invasive transforaminal interbody fusion (MI-TLIF), have been introduced to reduce approach-related muscle trauma, to minimise blood loss, and to achieve faster wound healing, quicker ambulation and earlier patient discharge.
Methods: The aim of this article was to give a comprehensive review of the available English literature comparing open TLIF with MI-TLIF techniques published or available online between 1990 and 2014 as identified by an electronic database search on http://www.
Purpose: We analyzed the lumbosacral segmental geometry and clinical outcome in patients undergoing L5 corpectomy.
Methods: Fourteen consecutive patients who underwent L5 (n = 12) or L4 + 5 (n = 2) corpectomy at our department between January 2010 and April 2015 were included. All patients underwent a baseline physical and neurologic examination on admission.
Purpose: There is a lack of studies highlighting the outcome by different scores or parameters after surgery for recurrent disc herniations of the lumbar spine at the initial herniation site. This study assessed the quality of life after surgical treatment of recurrent herniations with different standardized validated outcome instruments.
Methods: During a 24-month period, 64 patients underwent (microscope assisted) surgery for recurrent disc herniations of the lumbar spine.
Article Synopsis
- Preeclampsia is a pregnancy condition influenced by genetic, epigenetic, and environmental factors, leading to increased cell death (apoptosis) in the placenta.
- The study analyzed the expression of specific microRNAs (miR-155, miR-122, miR-21) in preeclamptic placentas compared to healthy ones, finding significant increases in these miRNAs in the affected samples.
- The findings suggest that the dysregulation of these miRNAs may impact the expression of their target mRNAs, potentially playing a role in the development of preeclampsia, and further research could clarify their functions in this disease.