Int J Cardiol Heart Vasc
June 2024
Background: In cardiogenic shock (CS), contractile failure is often accompanied by a systemic inflammatory response syndrome. In contrast, many patients with septic shock (SS) develop cardiac dysfunction. A similar hemodynamic support strategy is often deployed in both syndromes but it is unclear whether this is justified based on profiles of biomarkers expressing neurohormonal activation and cardiovascular stress.
View Article and Find Full Text PDFBackground: Combining the antibiotic azithromycin and hydroxychloroquine induces airway immunomodulatory effects, with the latter also having antiviral properties. This may improve outcomes in patients hospitalised for coronavirus disease 2019 (COVID-19).
Methods: Placebo-controlled double-blind randomised multicentre trial.