Neurodevelopmental outcome of preterm infants enrolled in myo-inositol randomized controlled trial.

Objective: This study evaluates the 24-month follow-up for the NICHD Neonatal Research Network (NRN) Inositol for Retinopathy Trial.

Study Design: Bayley Scales of Infants Development-III and a standardized neurosensory examination were performed in infants enrolled in the main trial. Moderate/severe NDI was defined as BSID-III Cognitive or Motor composite score <85, moderate or severe cerebral palsy, blindness, or hearing loss that prevents communication despite amplification were assessed.

Effects of Myo-inositol on Type 1 Retinopathy of Prematurity Among Preterm Infants <28 Weeks' Gestational Age: A Randomized Clinical Trial.

Importance: Previous studies of myo-inositol in preterm infants with respiratory distress found reduced severity of retinopathy of prematurity (ROP) and less frequent ROP, death, and intraventricular hemorrhage. However, no large trials have tested its efficacy or safety.

Objective: To test the adverse events and efficacy of myo-inositol to reduce type 1 ROP among infants younger than 28 weeks' gestational age.

Goniotomy versus circumferential trabeculotomy with an illuminated microcatheter in congenital glaucoma.

Purpose: To compare circumferential trabeculotomy performed with an illuminated microcatheter with standard goniotomy for the treatment of congenital glaucoma.

Methods: The short-term results of catheter-assisted trabeculotomy with an illuminated microcatheter were retrospectively compared with those of goniotomy in patients treated for congenital glaucoma. Success with either approach was defined as an intraocular pressure (IOP) <21 mm Hg with at least a 30% reduction from preoperative pressure levels at 12-month follow-up.

Circumferential trabeculotomy with an illuminated microcatheter in congenital glaucomas.

Purpose: To determine the safety and efficacy of circumferential trabeculotomy for congenital glaucomas using an illuminated microcatheter.

Methods: This was a retrospective chart study involving 11 eyes from 7 patients with primary or secondary congenital or juvenile glaucoma who underwent circumferential trabeculotomy performed with an illuminated microcatheter over a 2-year period. Data from eyes with 6 or more months of follow-up intraocular pressure (IOP) data were included in the analysis.

Masked trial of topical anesthesia for retinopathy of prematurity eye examinations.

Purpose: To observe the effect of a topical anesthetic on pain and corneal clarity in premature infants undergoing eye examinations for retinopathy of prematurity (ROP).

Methods: ROP examinations were performed on premature infants who were randomized to receive either proparacaine 0.5% or an artificial tear solution in the right eye.

Congenital osteoma cutis of the lateral canthus.

Osteoma cutis is a rare condition involving the formation of bone in skin or subcutaneous tissue. This may be a primary event or, more often, secondary to an inflammatory, traumatic, or neoplastic process. There is little evidence in the literature of this condition involving the eye or ocular adnexal structures.

Graded unilateral supramaximal medial rectus recession for moderate angle esotropia.

Background And Purpose: Recession of a single medial rectus muscle may be appropriate for certain cases of esotropia. However, the procedure has not been widely accepted nor widely studied, and most reports have dealt with conventional recessions (3.5-6 mm) for small angle esotropia.

Elimination of paradoxical diplopia following treatment with botulinum toxin and prism.

Background: Paradoxical diplopia occurs when binocular visual cerebral cortex projection of diplopic images (the "subjective angle") is not commensurate and identical with angle or direction of strabismus (the "objective angle"). Its presence infers anomalous retinal correspondence and is manifest as heteronymous or crossed diplopia in esotropia and homonymous or uncrossed diplopia in exotropia. When treated, the prognosis for achieving fusion is poor, while the risk for intractable diplopia is reputedly high.

Combined superior oblique tuck and adjustable suture recession of the ipsilateral superior rectus for long-standing superior oblique palsy.

Purpose: Unilateral long-standing superior oblique palsy may lead to superior rectus overaction/contracture requiring surgery of multiple extraocular muscles to correct the hypertropia. We review our technique of tucking the superior oblique combined with immediate postoperative adjustable suture recession of the ipsilateral superior rectus.

Methods: Twelve patients during the course of 2.

The immediate postoperative adjustment of sutures in strabismus surgery with comaintenance of anesthesia using propofol and midazolam.

Purpose: Adjustable suture techniques are used to reduce the reoperation rate in strabismus surgery, but traditionally require that final adjustments be made between 1 to 24 hours after surgery. The purpose of this study was to evaluate a new anesthetic technique that would allow immediate postoperative adjustment of sutures in strabismus surgery, thereby improving patient convenience and comfort.

Methods: This was a prospective study of strabismus patients who were judged to be appropriate candidates for adjustable sutures.