Publications by authors named "Martin Piepkorn"
Article Synopsis
- - The study aimed to examine the clinical presentations, imaging characteristics, and outcomes of children diagnosed with autoimmune encephalitis (AE) linked to myelin oligodendrocyte glycoprotein antibodies (MOG abs).
- - Researchers reviewed medical charts and conducted testing on ten children aged 4 to 16 years who tested positive for serum MOG abs, finding common symptoms like encephalopathy, headaches, and seizures, along with notable CSF changes and specific brain imaging results.
- - Most children had good outcomes after treatment, but some experienced additional demyelinating relapses, leading to the conclusion that MOG abs testing should be considered in suspected cases of AE in pediatric patients.
We retrospectively evaluated predictors of conversion to multiple sclerosis (MS) in 357 children with isolated optic neuritis (ON) as a first demyelinating event who had a median follow-up of 4.0 years. Multiple Cox proportional-hazards regressions revealed abnormal cranial magnet resonance imaging (cMRI; hazard ratio [HR] = 5.
View Article and Find Full Text PDFRecent advances have revealed significant differences in the pathogenesis of inflammatory myopathies. To determine whether different patterns of macrophage differentiation are a useful tool to delineate the major groups of inflammatory myopathies, the muscle biopsies of 11 patients with dermatomyositis and 12 patients with polymyositis were studied using different macrophage markers. In polymyositis, the early-activation markers MRP14 and 27E10 stained the majority of macrophages, which were recognized by the pan-macrophage marker Ki-M1P and which were located primarily in the endomysium.
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