Five-year results from a prospective, single-arm European trial on decellularized allografts for aortic valve replacement-the ARISE Study and ARISE Registry Data.

Objectives: Decellularized aortic homografts (DAH) were introduced as a new option for aortic valve replacement for young patients.

Methods: A prospective, EU-funded, single-arm, multicentre study in 8 centres evaluating non-cryopreserved DAH for aortic valve replacement.

Results: A total of 144 patients (99 male) were prospectively enrolled in the ARISE Trial between October 2015 and October 2018 with a median age of 30.

Percutaneous large-bore aspiration embolectomy with veno-arterial extracorporal membrane oxygenation support or standby in patients with high-risk pulmonary embolism and contraindications to thrombolysis: a preliminary single centre experience.

Aims: Large-bore catheter aspiration embolectomy reduces thrombus burden and right ventricle strain and improves haemodynamics after pulmonary embolism (PE). Sparse data are available for patients with high-risk PE and contraindications to thrombolysis or thrombolysis failure, particularly if veno-arterial extracorporal membrane oxygenation (VA-ECMO) is required.

Methods And Results: All patients with acute high-risk PE and contraindications to thrombolysis undergoing FlowTriever® percutaneous embolectomy and VA-ECMO circulatory support (or standby) at the University Hospital Zurich between April 2021 and August 2022 were retrospectively analysed.

Feasibility and Safety of Cerebral Embolic Protection Device Insertion in Bovine Aortic Arch Anatomy.

Background: Cerebral embolic protection devices (CEPDs) have emerged as a mechanical barrier to prevent debris from reaching the cerebral vasculature, potentially reducing stroke incidence. Bovine aortic arch (BAA) is the most common arch variant and represents challenge anatomy for CEPD insertion during transcatheter aortic valve replacement (TAVR).

Methods: Cohort study reporting the Sentinel Cerebral Protection System insertion's feasibility and safety in 165 adult patients submitted to a transfemoral TAVR procedure from April 2019 to April 2020.

Modified cardiopulmonary bypass circuit for the use of the AngioVac® system in a case with high paradoxical embolization risk.

The AngioVac is a vacuum-assisted percutaneous thrombectomy suction system. In critically ill patients, the sudden volume shift can result in abrupt hemodynamic changes thus leading to a cardiac right-left shunt with a high risk of paradoxical embolization. We describe a modified cardiopulmonary bypass circuit for the use of the AngioVac system that enables full cardiopulmonary support and reduces paradoxical thromboembolic risk.

Do all roads lead to Rome? Treatment of malposition pacemaker lead in the left ventricle.

Malpositioning of a pacemaker lead in the left ventricle is a rare device-related complication, which can lead to serious complications. Herein, we describe the case of a malpositioned lead, which entered the left ventricle via a direct transcutaneous puncture of the left common carotid artery.