Publications by authors named "Martin McPhilimey"
The influence of oxidative stress, diaphragm fatigue, and inspiratory muscle training (IMT) on the cytokine response to maximum sustainable voluntary ventilation (MSVV) is unknown. Twelve healthy males were divided equally into an IMT or placebo (PLA) group, and before and after a 6-wk intervention they undertook, on separate days, 1 h of (1) passive rest and (2) MSVV, whereby participants undertook volitional hyperpnea at rest that mimicked the breathing and respiratory muscle recruitment patterns commensurate with heavy cycling exercise. Plasma cytokines remained unchanged during passive rest.
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- Researchers explored if respiratory muscles affect exercise-induced increases in plasma interleukin-6 (IL-6) levels, particularly during diaphragm fatigue and with inspiratory muscle training (IMT).
- A study with 12 healthy males found that IMT decreased IL-6 response to actual exercise but not to simulated hyperpnea, while no diaphragm fatigue was detected during any trial.
- Results indicated that both exercise and hyperpnea elevate IL-6 levels, and that IMT can moderate this response to real exercise but not to mimicked conditions.
Background: This study was conducted to examine the effect of oral contraceptives on endogenous reproductive hormone levels in order to assess the suitability of oral contraceptive users as experimental and/or control groups in human performance studies.
Study Design: Ninety-five females who were taking a variety of oral contraceptives (2 types and 11 brands) were recruited. A single blood sample was analysed for endogenous concentrations of oestradiol and progesterone.