[Rational use of psychotropic medications and sedative load in older adults with and without dementia].

Unlabelled: Sedative drugs use has been associated with more cognitive impairment and increased mortality. Sedative load refers to cumulative exposure to multiple drugs with sedative properties.

Objective: Describe the use of psychotropic drugs and sedative load in older adults with and without dementia.

Pseudodystonic Posture Secondary to Klippel-Feil Syndrome and Diastematomyelia.

Background: Dystonic postures possess a great number of differential diagnoses.

Phenomenology Shown: We describe a pseudodystonic posture in a 61-year-old woman with skeletal and extra-skeletal abnormalities.

Educational Value: Klippel-Feil syndrome represents an unusual cause of pseudodystonic posture to be considered in the differential diagnosis of dystonia.

Endothelinergic cells in the subependymal region of mice.

Endothelin (ET) is a small peptide that activates astrocyte proliferation, regulates proliferation and migration of embryonic neural precursor cells and stimulates glioblastoma growth. We found that in mouse brain, ET and its receptor B (ETRB) were highly expressed in the subependymal zone (SEZ), an adult neurogenic niche. Cells with ET immunoreactivity (ET+ cells) selectively appeared along the lateral and dorsal walls of the lateral ventricle.