Aerosol Release by Healthy People during Speaking: Possible Contribution to the Transmission of SARS-CoV-2.

Our research aimed to review the potential risk of infection by SARS-CoV-2. We used an excerpt of a data set generated in May 2020 for reviewing the SARS-CoV-2 prevention concept of orchestras, singers and actors. People were sampled for droplet release for one-hour activities using a Grimm spectrometer covering a spectrum of 1 to 32 µm diameter.

Classification of dermal sensitizers in pharmaceutical manufacturing.

Workers in development and manufacturing of pharmaceuticals are at risk for occupational contact dermatitis (OCD) of irritative (ICD) or allergic (ACD) origin, due to contacts with reactive intermediates (IM) and drug substances (DS). We examined, if alternative methods could replace presently used animal tests for identification of ACD in pharmaceutical development and manufacturing, without apparent loss of worker health, in line with regulations. The status of alternative methods for regulatory toxicology for consumer products has recently been reviewed by the Organisation for Economic Co-operation and Development (OECD) and the European Commission's Joint Research Center (JRC) for the European Chemicals Agency (ECHA).

Predictors of marked weight gain in a population of health care and industrial workers following smoking cessation.

Background: Concerns about postcessational weight gain might hamper rather than encourage smokers to quit smoking.

Methods: We conducted a comprehensive multi-institutional smoking cessation program for health care and industrial workers (n = 654) employed at University Hospital Basel (Switzerland) and two local health industry companies (Novartis International AG, F. Hoffmann-La Roche AG).

Cancer risk of immunosuppressants in manufacturing.

During the chemical and pharmaceutical production of active pharmaceutical substances which are intended for immunosuppressive therapy, the employees may be exposed to these substances via inhalation. Immunosuppressants are linked to development of certain types of cancers e.g.

Predictors of success for smoking cessation at the workplace: a longitudinal study.

Background: The effectiveness of worksite interventions to reduce smoking is debatable.

Objectives: A comprehensive smoking cessation intervention was implemented in a community of more than 17,000 employees at three different health care companies. The primary endpoint was abstinence at 24 months (self-reported and confirmed by exhaled carbon monoxide ≤ 6 parts per million).

Estimating the direct-to-reverberant energy ratio from the coherence between coincident pressure and particle velocity.

An analytical expression for the relationship between the direct-to-reverberant energy ratio (DRR) and the coherence estimation function between coincident pressure and particle velocity component is derived. The analytical solution is first validated with simulated room impulse responses and then used to estimate the DRR in five octave bands for several receiver positions measured in a total of 11 rooms of vastly different sizes and acoustic characteristics. The accuracy is evaluated by comparison with the DRR estimated directly from the room impulse response.

Reliability of estimating the room volume from a single room impulse response.

The methods investigated for the room volume estimation are based on geometrical acoustics, eigenmode, and diffuse field models and no data other than the room impulse response are available. The measurements include several receiver positions in a total of 12 rooms of vastly different sizes and acoustic characteristics. The limitations in identifying the pivotal specular reflections of the geometrical acoustics model in measured room impulse responses are examined both theoretically and experimentally.

Spatial correlation and coherence in reverberant acoustic fields: Extension to microphones with arbitrary first-order directivity.

Spatial correlation and coherence functions in reverberant sound fields are relevant to the acoustics of enclosed spaces and related areas. Theoretical expressions for the spatial correlation and coherence functions between signals representing the pressure and/or the components of the particle velocity vector in a reverberant sound field are established in the literature and most of these have also been corroborated with measurements [F. Jacobsen, J.