Active vaccination against interleukin-5 as long-term treatment for insect-bite hypersensitivity in horses.

Background: Insect-bite hypersensitivity (IBH) in horses is a chronic allergic dermatitis caused by insect bites. Horses suffer from pruritic skin lesions, caused by type-I/type-IV allergic reactions accompanied by prominent eosinophil infiltration into the skin. Interleukin-5 (IL-5) is the key cytokine for eosinophils and we have previously shown that targeting IL-5 by vaccination reduces disease symptoms in horses.

Treating insect-bite hypersensitivity in horses with active vaccination against IL-5.

Background: Insect-bite hypersensitivity is the most common allergic dermatitis in horses. Excoriated skin lesions are typical symptoms of this seasonal and refractory chronic disease. On a cellular level, the skin lesions are characterized by massive eosinophil infiltration caused by an underlying allergic response.

Salter-Harris type II metacarpal and metatarsal fracture in three foals. Treatment by minimally-invasive lag screw osteosynthesis combined with external coaptation.

Objectives: To describe minimally-invasive lag screw osteosynthesis combined with external coaptation for the treatment of Salter-Harris type II third metacarpal and third metatarsal bone fractures.

Methods: Three foals aged two weeks to four months with a Salter-Harris type II third metacarpal or third metatarsal fracture. Surgery was carried out under general anaesthesia in lateral recumbency.

Arthroscopically accessible anatomy of the tarsal collateral ligaments in the horse.

Objective: To describe the arthroscopically accessible anatomy of the tarsal collateral ligaments in the horse.

Study Design: Descriptive study.

Animals: Cadaveric equine hind limbs (n = 24) obtained from horses without tarsal disease.

Endoscopic-assisted electrohydraulic shockwave lithotripsy in standing sedated horses.

Objective: To report use of transendoscopic electrohydraulic shockwave lithotripsy for fragmentation of urinary calculi in horses.

Study Design: Case series.

Animals: Male horses (n = 21).

Locking compression plate osteosynthesis of sacral fractures in three heifers.

Objective: To describe a technique used for reduction and internal fixation of sacral fractures in cattle.

Study Design: Case series.

Animals: Three heifers aged 19-32 months with deformation of the tail head and tail paralysis attributable to a closed fracture of S5 or S4 and S5.

Evaluation of a motorized morcellator for laparoscopic removal of granulosa-theca cell tumors in standing mares.

Objective: To describe a motorized morcellator technique for laparoscopic removal of granulosa-theca cell tumors (GCT) in standing mares and to evaluate long-term outcome.

Study Design: Case series.

Animals: Mares (n=7) aged 4-15 years, with unilateral GCT.

Ventral locking compression plate for treatment of cervical stenotic myelopathy in a 3-month-old warmblood foal.

Objective: To report a novel technique for cervical vertebral fusion in a foal with cervical vertebral malformation (CVM).

Study Design: Case report.

Methods: A 3-month-old Warmblood filly with ataxia, weakness, and stenotic myelopathy at the level of the articulation of the 6th (C6) and 7th (C7) cervical vertebrae had a 7-hole broad locking compression plate (LCP) applied to the ventral aspect of C6 and C7 using seven 5.

Evaluation of anesthesia recovery quality after low-dose racemic or S-ketamine infusions during anesthesia with isoflurane in horses.

Objective: To compare anesthesia recovery quality after racemic (R-/S-) or S-ketamine infusions during isoflurane anesthesia in horses.

Animals: 10 horses undergoing arthroscopy.

Procedures: After administration of xylazine for sedation, horses (n = 5/group) received R-/S-ketamine (2.

Comparison of the trimming procedure of six different farriers by quantitative evaluation of hoof radiographs.

Hoof preparation and shoe fit are integral to the long term soundness and athletic ability of horses. The farrier influences the balance of the hoof by both the trimming and the shoeing procedure. The goal of this study was to investigate and quantify the influence of the farrier on hoof parameters by trimming.

The effect of hoof trimming on radiographic measurements of the front feet of normal Warmblood horses.

The understanding of the normal position of the third phalanx (P3) and the distal sesamoid bone in relation to the size and shape of the hoof capsule in sound horses is helpful in the diagnosis of equine foot lameness. Some measurements on radiographs used to define the position of the pedal bone within the hoof capsule are significantly influenced by hoof trimming and the height of the withers. In this study, the front hooves of 40 Warmblood horses were radiographed twice, eight weeks apart, both before and after their hooves were trimmed by an experienced farrier.