Publications by authors named "Martin Jede"
Article Synopsis
- Sterols are common compounds found in cell membranes and are resistant to breakdown due to their water-insoluble nature; a new pathway for degrading cholesterol has been discovered in the bacterium Sterolibacterium denitrificans.
- This pathway includes a series of ATP-dependent enzyme reactions that modify sterol structures, specifically targeting cholesterol while being unsuitable for other steroids like stigmasterol.
- Researchers identified a key enzyme from S. denitrificans that facilitates the oxidation of sterol intermediates, ultimately enabling a process to hydroxylate the isoprenoid side chain without requiring oxygen, thus presenting a novel method for sterol degradation.
