Publications by authors named "Martin Igaz"
Article Synopsis
- The study investigates the role of the retinoblastoma (RB) pathway in breast cancer (BC) progression by comparing protein expression in primary tumors and matched lymph node metastases (LM).
- Using immunohistochemistry, researchers analyzed proteins such as cyclin D1, CDK4/6, RB, pRB, and E2F1 to assess their expression levels in tissue samples from 50 patients.
- The findings revealed that pRB and E2F1 were significantly more expressed in LM compared to primary BC, indicating alterations in the RB pathway may be linked to cancer metastasis and could influence chemotherapy strategies for patients with limited LM.
B7-H3 is a transmembrane protein and a member of the B7 family of immune regulatory ligands. It exerts both inhibitory and stimulatory effects on the activation of T cells. We investigated the expression of B7-H3 in invasive squamous cell carcinoma (ISCC) of the uterine cervix by immunohistochemistry, and aimed to determine whether expression of this factor is involved in the progression of the morphologic spectrum from normal cervical epithelia to cervical intraepithelial neoplasia and cervical ISCC.
View Article and Find Full Text PDFRole of endotracheal stenting in tracheal reconstruction surgery-retrospective analysis.
Eur J Cardiothorac Surg
June 2004
Objective: To review a single institution experience with tracheal stenosis treatment and to define a role of endotracheal stenting in tracheal reconstruction surgery.
Patients And Methods: In the period between January 1991 and January 2003, 163 patients underwent tracheal reconstruction. There were 114 males and 49 females in age range from 0.