Publications by authors named "Martin Hong"
Background: Cancer care coordinators (CCCs) are recognized as having an important role in patients' and carers' cancer journey. However, there are no studies investigating the impact of CCCs on quantitative outcomes. We performed a retrospective cohort study investigating the impact of brain cancer care coordinators (BCCCs) on health service resource use and survival in patients with glioblastoma.
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- Early phase clinical trials (EPCTs) are essential for providing new treatments to patients with limited options, but culturally and linguistically diverse (CALD) and socially disadvantaged patients have lower participation rates in these trials.* -
- A 10-year review of 233 patients at Liverpool Hospital showed that 39% were CALD, with a significant percentage living in areas of socioeconomic disadvantage, indicating a disconnect between trial participants and the local population.* -
- The findings highlight the underrepresentation of CALD patients in EPCTs and suggest that their socioeconomic status may influence their access to these clinical trials, calling for strategies to improve participation.*
Article Synopsis
- The study evaluates different prognostic scoring systems to predict survival in patients participating in early phase clinical trials for advanced cancer at Liverpool Hospital between 2013 and 2023.
- Data from 218 patients revealed an overall median survival of 9.8 months, with a notable 22% experiencing death within 90 days, while 17-34% were classified as high-risk.
- Among the five scoring systems tested, the MD Anderson Cancer Center score showed the best predictive ability, but all systems were similarly effective, suggesting that these scores could enhance patient selection in clinical trials.
Melanoma gave science a window into the role immune evasion plays in the development of malignancy. The entire spectrum of immune focused anti-cancer therapies has been subjected to clinical trials in this disease, with limited success until the immune checkpoint blockade era. That revolution launched first in melanoma, heralded a landscape change throughout cancer that continues to reverberate today.
View Article and Find Full Text PDFAim: We performed the first study on the perceived benefit and adverse effects of symptomatic management in children with anti-N-methyl-d-aspartate receptor (NMDAR) encephalitis.
Method: A retrospective chart review was undertaken at two tertiary paediatric hospitals in Australia and New Zealand. We included 27 children (12 males, 15 females; mean age at admission 7y 1mo) with anti-NMDAR antibodies in serum or cerebrospinal fluid with a typical clinical syndrome.
Background: People with chronic kidney disease (CKD) have an increased risk of stroke but the magnitude of increased risk and the independent effects of glomerular filtration rate (GFR) and albuminuria are unclear. We aimed to quantify the association between the independent and combined effects of GFR and albuminuria on stroke risk.
Methods: We searched MEDLINE and EMBASE (February 2014) for cohort studies or randomized controlled trials (RCTs) which reported stroke incidence in adults with a baseline measurement of GFR and/or albuminuria.