J Clin Endocrinol Metab
July 2007
Context: Activating transcription factor 6 (ATF6) is critical for initiation and full activation of the unfolded protein response. An association between genetic variation in ATF6 and type 2 diabetes (DM2) was recently reported in Pima Indians.
Objectives: To investigate the broader significance of this association for DM2, replication studies in distinct ethic populations are required.