Viable acrosome-intact human spermatozoa in the ejaculate as a marker of semen quality and fertility status.

Study Question: Is it possible, in an unbiased and clinical relevant way, to determine the number of viable acrosome-intact human spermatozoa in ejaculates and to use this as a measure of fertility chances?

Summary Answer: Image cytometry enables easy and unbiased quantification of viable acrosome-intact spermatozoa and it correlates with semen quality and fertility status.

What Is Known Already: The presence of the acrosome and its ability to respond to physiological inducers (e.g.