Publications by authors named "Martin Fuhrer"
Introduction: Reconstitution of peripheral blood (PB) B cells after therapeutic depletion with the chimeric anti-CD20 antibody rituximab (RTX) mimics lymphatic ontogeny. In this situation, the repletion kinetics and migratory properties of distinct developmental B-cell stages and their correlation to disease activity might facilitate our understanding of innate and adaptive B-cell functions in rheumatoid arthritis (RA).
Methods: Thirty-five 'RTX-naïve' RA patients with active arthritis were treated after failure of tumour necrosis factor blockade in an open-label study with two infusions of 1,000 mg RTX.
Article Synopsis
- Determining the right clinical monitoring parameters is critical in managing severe head injuries in intensive care.
- Recent research suggests that a fixed cerebral perfusion pressure may not be effective for all patients, prompting the development of a new online analysis technique to evaluate the relationship between mean arterial blood pressure and intracranial pressure.
- Findings indicate that lower AI rho values and higher glucose and lactate levels in brain tissue are associated with better outcomes, suggesting that AI rho could be a useful tool in guiding treatment.