Factors influencing adverse perinatal outcomes in pregnancies achieved through use of in vitro fertilization.

Objective: To determine the associations of specific components of IVF treatment with abnormal perinatal outcomes.

Design: Case-control study.

Setting: University-based and community-based infertility centers.

Defining the rise of serum HCG in viable pregnancies achieved through use of IVF.

Background: We aimed to characterize the rate of HCG rise associated with viable IVF pregnancies, and to evaluate the association between HCG rise and potentially influential factors.

Methods: We performed a retrospective cohort analysis of all viable pregnancies achieved through IVF at two centres between January 1999 and March 2004.

Results: Of the 455 pregnancies resulting in live births, 391 met inclusion criteria and contributed a total of 1052 HCG values.

Exacerbation of ovarian hyperstimulation by leuprolide reveals a gonadotroph adenoma.

Objective: To report a case of a gonadotroph adenoma diagnosed after a dramatic increase in estradiol level and ovarian hyperstimulation in response to a gonadotropin-releasing hormone agonist.

Design: Case report.

Setting: Outpatient practice and university hospital.