Modified Edmonton Symptom Assessment System including constipation and sleep: validation in outpatients with cancer.

Context: The Edmonton Symptom Assessment System (ESAS) measures the severity of nine symptoms. Constipation and sleep disturbance are common in patients with cancer, but are not currently included in the ESAS.

Objectives: To validate the numerical rating scale (NRS) versions of ESAS and its revised version (ESAS-r), with the additional symptoms of constipation and sleep (CS), and to assess patient preference for either version.

Rapid point-of-care HIV testing in youth: a systematic review.

Purpose: This review examines the literature surrounding acceptability of, and preference for, rapid point-of-care (POC) human immunodeficiency virus (HIV) testing in youth, documents notification rates when youth were offered rapid POC testing, and identifies the sociodemographic factors associated with testing.

Methods: The reviewers searched the scholarly literature indexed in MEDLINE, Embase, CINAHL, and PsycInfo using a set of keywords related to youth and rapid POC HIV testing. A total of 14 articles were included in the review.

The anticancer effects of Vitamin D and omega-3 PUFAs in combination via cod-liver oil: one plus one may equal more than two.

In the past number of years, the anticancer activities of omega-3 polyunsaturated fatty acids (ω3-PUFAs) as well as Vitamin D have been intensively studied, but separately. Supplementation of Vitamin D and omega-3 PUFA via cod-liver oil, one of few natural sources of both of these molecules, may have additive and possibly synergistic anticancer effects. Cod-liver oil has been used effectively to treat diseases such as Rheumatism but has not been studied as an anticancer agent.