Publications by authors named "Martin Cearras"
Purpose: Endothelial and platelet microparticles (eMPs and pMPs), markers of cellular activation, dysfunction, or apoptosis, have been associated with multiple cardiovascular conditions. Chronic obstructive pulmonary disease (COPD) is associated with cardiovascular comorbidities and platelet/endothelial dysfunction. We analyzed whether eMPs and pMPs are associated with COPD status and/or severity.
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- The study examines the characteristics and outcomes of 131 patients with severe COVID-19 who were admitted to the ICU in Florida, revealing a median age of 61 and common comorbidities such as hypertension and diabetes.
- Among the ICU patients, 83.2% required mechanical ventilation, with survivors showing significant differences in ventilator settings and longer lengths of stay compared to non-survivors.
- Overall hospital and mechanical ventilation-related mortality rates were found to be 19.8% and 23.8%, indicating critical challenges in managing severe COVID-19 cases in the ICU.
High-dose erythropoietin has been claimed to be cardioprotective in experimental acute myocardial infarction. In large mammals, however, results are controversial and long-term follow-up data are lacking. We thus assessed the long-term effects of high-dose erythropoietin on left ventricular infarct size and function in an ovine model of reperfused myocardial infarction.
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