Pharyngeal Electrical Stimulation favorably modifies healthy human pharyngo-esophageal function - a randomized trial using High Resolution Manometry Impedance.

Background: Despite positive clinical evidence for the effects of Pharyngeal Electrical Stimulation (PES) on swallowing performance in disease, it remains unknown which specific swallow characteristics improve. Using High Resolution Manometry Impedance (HRMI) with Pressure Flow Analysis (PFA), we aimed to assess the effects of PES on normal swallow function and to evaluate the impact of pharyngeal length variability on electrode placement.

Methods: As part of a prospective RCT, 20 asymptomatic volunteers were randomly assigned to three days of PES or SHAM treatment.