Artemether-Lumefantrine Efficacy for the Treatment of Uncomplicated Malaria in Choco, Colombia after 8 Years as First-Line Treatment.

Artemether-lumefantrine (AL) is the first-line treatment for uncomplicated infection in Colombia. To assess AL efficacy for uncomplicated falciparum malaria in Quibdo, Choco, Colombia, we conducted a 28-day therapeutic efficacy study (TES) following the WHO guidelines. From July 2018 to February 2019, febrile patients aged 5-65 years with microscopy-confirmed mono-infection and asexual parasite density of 250-100,000 parasites/µL were enrolled and treated with a supervised 3-day course of AL.