Association between change in self-reported sugar intake and a sugar biomarker (δC) in children at increased risk for type 1 diabetes.

We examined whether change in added sugar intake is associated with change in δC, a novel sugar biomarker, in thirty-nine children aged 5-10 years selected from a Colorado (USA) prospective cohort of children at increased risk for type 1 diabetes. Reported added sugar intake via FFQ and δC in erythrocytes were measured at two time points a median of 2 years apart. Change in added sugar intake was associated with change in the δC biomarker, where for every 1-g increase in added sugar intake between the two time points, there was an increase in δC of 0⋅0082 ( = 0⋅0053), independent of change in HbA1c and δN.