Publications by authors named "Martha Lewerenz"
Article Synopsis
- Aromatase inhibitors like letrozole, which lower estradiol levels, may cause memory issues in women by inducing changes in the brain.
- Letrozole treatment in female mice led to a rapid decline in long-term potentiation (LTP) and cofilin phosphorylation, both important for memory formation and maintenance.
- The study found that the negative effects on brain structure and function were similar in both female and male mice, but the response intensity varied between genders, suggesting significant implications for memory impairments in women using letrozole.
