Publications by authors named "Martha Kordulla"
Psychiatry Res
January 2013
Article Synopsis
- Major depression disorder (MDD) is a leading cause of disability for individuals over 60, and its impact on cognitive function is linked to white matter (WM) disruption in the brain.
- A study compared WM integrity, measured by fractional anisotropy (FA), in 17 elderly MDD patients and 18 similar-aged controls, revealing lower FA in the right posterior cingulate cluster among those with MDD.
- Findings indicated that lower FA in the right PCC correlated with better performance on verbal naming tasks in MDD patients, suggesting cognitive deficits may stem from WM integrity loss, while controls showed no such correlations.
