Psychometric properties of the Dutch version Adult Strabismus-20 Questionnaire (AS-20).

Purpose: Strabismus often has an impact on a patient's quality of life (QoL). The Adult Strabismus-20 questionnaire (AS-20) is an instrument developed to assess the strabismus-specific QoL. The aim was to investigate several psychometric properties of the Dutch-AS-20 among adult patients with strabismus.

Ectopia lentis et pupillae in four generations caused by novel mutations in the ADAMTSL4 gene.

Objectives: To identify the phenotype, genetic defect and inheritance pattern of ectopia lentis et pupillae (ELP) in a large Dutch family, previously diagnosed as presumed autosomal dominant ELP because of the occurrence of ELP in three generations.

Design: A clinical and genetic study of children and adults.

Participants: Eight patients of the ELP family, including five new patients from the youngest generation.

Cyclotorsion: a possible cause of residual astigmatism in refractive surgery.

Purpose: To determine whether cyclotorsion occurs when a subject changes from binocular to monocular fixation and to assess positionally induced cyclotorsion.

Setting: Clinics of the Rotterdam Eye Hospital, Rotterdam, The Netherlands.

Methods: The axis of astigmatism was measured with the Nidek handheld keratometer in 15 normal subjects under monocular and binocular fixation and in seated and supine positions.