Ascorbate- and zinc-responsive parkinsonism.

Objective: To report a case of Parkinsonism rapidly responsive to intravenous replacement of vitamin C and zinc.

Case Summary: A 66-year-old man with Parkinsonism, pleural effusion, and bipolar disorder was found to have low serum vitamin C and zinc levels. Intravenous replacement of these micronutrients led to resolution of the movement disorder in less than 24 hours.