Flow cytometric-based detection of CD80 is a useful diagnostic marker of acute myeloid leukemia in dogs.

Introduction: CD80, a co-stimulatory molecule required for optimal T cell activation, is expressed on antigen-presenting cells, including monocytes and dendritic cells, in dogs and humans. We hypothesized that CD80 would be expressed on tumor cells in dogs from acute myeloid leukemia (AML) but not dogs with lymphoid neoplasms.

Methods And Results: We first evaluated the cellular staining pattern of a hamster anti-murine CD80 antibody (clone 16-10A1, ThermoFisher Scientific Cat# 17-0801-82, RRID: AB_469417) in blood and bone marrow aspirates from healthy dogs.

Transient increases in glutamate dehydrogenase (GLDH) activity occur in neonatal foals.

Background: Liver analyte measurement is important in the evaluation of sick animals. Liver injury in horses is recognized by increased glutamate dehydrogenase (GLDH), sorbitol dehydrogenase (SDH), and aspartate aminotransferase (AST) activities, whereas biliary pathology is identified by increased alkaline phosphatase and γ-glutamyl transferase (GGT) activities or bilirubin concentrations. We have observed high GLDH, but not SDH, activities in neonatal foals admitted for conditions other than liver disease.

The Male Voice: A Qualitative Assessment of Young Men's Communication Preferences About HPV and 9vHPV.

In the U.S. there is an epidemic of sexually transmitted diseases (STIs).

Integrative learning strategies.

Integrative teaching strategies that include nurses' clinical stories provide an opportunity to clarify learning needs and support a comfortable climate to share, reflect, and learn.