A novel multifamily treatment targeting symptoms related to Latinx caregiver deportation.

Objective: Latinx youth who have experienced caregiver deportation show higher rates of posttraumatic stress disorder (PTSD) and internalizing symptoms compared to Latinx youth who have not. Thus, there is a need for culturally and linguistically appropriate therapeutic approaches to address psychiatric needs related to caregiver deportation. Positive Adaptations for Trauma and Healing (PATH) is a manualized 10-week group therapy for Latinx youth and their caregivers that integrates trauma-informed interventions with positive psychology and resilience interventions.

A model of collaborative immigration advocacy to prevent policy-based trauma and harm.

Objective: Research suggests that antiimmigrant policies enacted in the United States, magnified during the 2016-2020 period, propagate widespread trauma across communities of immigrants (von Werthern et al., 2018). While these policies harm all groups of immigrants, structural conditions (e.

Phytotoxic activity of , an invasive plant on Chilean ecosystems: separation and identification of potential allelochemicals.

Despite its worldwide relevance as an invasive plant, there are few studies on (gorse) and its allelopathic activity is almost unexplored. The allelochemical profile of gorse was analysed through methanolic extract of pods and roots, and its phytotoxic effects on germination. The methanolic extract of pods had no effect in germination, while extract of roots resulted in a U-shaped dose-response curve: reducing the germination at concentration 0.

Pediatric multisystem SARS COV2 with versus without cardiac involvement: a multicenter study from Latin America.

Latin America (LATAM) children offer special insight into Severe Acute Respiratory Syndrome Coronavirus 2 (SARS COV2) due to high-risk race/ethnicity, variability in medical resources, diverse socioeconomic background, and numerous involved organ systems. This multinational study of LATAM youth examined the distinguishing features of acute or late multisystem SARS COV2 with versus without cardiac involvement. A consecutive sample of youth 0-18 years old (N = 98;50% male) presenting with multisystem SARS COV2 to 32 centers in 10 Latin American countries participating in a pediatric cardiac multi-imaging society were grouped as with versus without cardiac involvement, defined as abnormal echocardiographic findings or arrhythmia.

Perceptual impact of astigmatism induction in presbyopes.

We investigated the effect of induced astigmatism on subjective best focus and on visual acuity in 28 subjects of different ages (pre-presbyopic and presbyopic) and with different refractive profiles (emmetropes and astigmats). Measurements were performed using a custom-developed Adaptive Optics system, which allowed correction of high order aberrations and induction of astigmatism (0.5, 1, 1.

Urban airborne particle exposure impairs human lung and blood immunity.

Rationale: Associations between urban (outdoor) airborne particulate matter (PM) exposure and TB and potential biological mechanisms are poorly explored.

Objectives: To examine whether in vivo exposure to urban outdoor PM in Mexico City and in vitro exposure to urban outdoor PM (< 2.5 µm median aerodynamic diameter) alters human host immune cell responses to .

Impact of astigmatism and high-order aberrations on subjective best focus.

We studied the role of native astigmatism and ocular aberrations on best-focus setting and its shift upon induction of astigmatism in 42 subjects (emmetropes, myopes, hyperopes, with-the-rule [WTR] and against-the-rule [ATR] myopic astigmats). Stimuli were presented in a custom-developed adaptive optics simulator, allowing correction for native aberrations and astigmatism induction (+1 D; 6-mm pupil). Best-focus search consisted on randomized-step interleaved staircase method.

Influence of spherical aberration, stimulus spatial frequency, and pupil apodisation on subjective refractions.

Purpose: To test competing hypotheses (Stiles Crawford pupil apodising or superior imaging of high spatial frequencies by the central pupil) for the pupil size independence of subjective refractions in the presence of primary spherical aberration.

Methods: Subjective refractions were obtained with a variety of test stimuli (high contrast letters, urban cityscape, high and low spatial frequency gratings) while modulating pupil diameter, levels of primary spherical aberration and pupil apodisation. Subjective refractions were also obtained with low-pass and high-pass stimuli and using 'darker' and 'sharper' subjective criteria.

Evaluation of a global algorithm for wavefront reconstruction for Shack-Hartmann wave-front sensors and thick fundus reflectors.

Purpose: Conventional aberration analysis by a Shack-Hartmann aberrometer is based on the implicit assumption that an injected probe beam reflects from a single fundus layer. In fact, the biological fundus is a thick reflector and therefore conventional analysis may produce errors of unknown magnitude. We developed a novel computational method to investigate this potential failure of conventional analysis.

Astigmatism impact on visual performance: meridional and adaptational effects.

Purpose: Astigmatic subjects are adapted to their astigmatism and perceptually recalibrate upon its correction. However, the extent to which prior adaptation to astigmatism affects visual performance, whether this effect is axis dependent, and the time scale of potential changes in visual performance after astigmatism correction are not known. Moreover, the effect of possible positive interactions of aberrations (astigmatism and coma) might be altered after recalibration to correction of astigmatism.

Anxiolytic-like effect of pregabalin on unconditioned fear in the rat: an autoradiographic brain perfusion mapping and functional connectivity study.

Clinical and preclinical evidence suggests anxiolytic-like efficacy of pregabalin (PGB, Lyrica). However, its mechanism of action remains under investigation. The current study applied [(14)C]-iodoantipyrine cerebral blood flow (CBF) mapping to examine the effect of PGB on neural substrates underlying unconditioned fear in a rat model of footshock-induced fear.

Roles of endonuclease V, uracil-DNA glycosylase, and mismatch repair in Bacillus subtilis DNA base-deamination-induced mutagenesis.

The disruption of ung, the unique uracil-DNA-glycosylase-encoding gene in Bacillus subtilis, slightly increased the spontaneous mutation frequency to rifampin resistance (Rif(r)), suggesting that additional repair pathways counteract the mutagenic effects of uracil in this microorganism. An alternative excision repair pathway is involved in this process, as the loss of YwqL, a putative endonuclease V homolog, significantly increased the mutation frequency of the ung null mutant, suggesting that Ung and YwqL both reduce the mutagenic effects of base deamination. Consistent with this notion, sodium bisulfite (SB) increased the Rif(r) mutation frequency of the single ung and double ung ywqL strains, and the absence of Ung and/or YwqL decreased the ability of B.

Visual acuity under combined astigmatism and coma: optical and neural adaptation effects.

Previous studies suggest that certain combinations of coma and astigmatism improve optical quality over astigmatism alone. We tested these theoretical predictions on 20 patients. Visual acuity (VA) was measured under best spherical correction for different conditions: low- and higher order aberrations corrected, in the presence of 0.

Combining coma with astigmatism can improve retinal image over astigmatism alone.

We demonstrate that certain combinations of non-rotationally symmetric aberrations (coma and astigmatism) can improve retinal image quality over the condition with the same amount of astigmatism alone. Simulations of the retinal image quality in terms of Strehl Ratio, and measurements of Visual Acuity under controlled aberrations with adaptive optics were performed, varying defocus, astigmatism and coma. Astigmatism ranged between 0 and 1.

Antimicrobial activity of the dichloromethane extract from in vitro cultured roots of Morinda royoc and its main constituents.

The dichloromethane extract and seven anthraquinones isolated from in vitro cultured roots of Morinda royoc L. were tested for their antimicrobial activity against seven yeast and seven bacterial strains. The extract showed a minimum inhibitory concentration (MIC) value of 15.

Metabolic Abnormalities in Abstinent Methamphetamine Dependent Subjects.

INTRODUCTION: Chronic methamphetamine use results in persistent neuropsychological deficits in abstinent methamphetamine dependent (AMD) subjects. We examined the hypothesis that elevated concentration of cerebral glutamate (Glu), an excitatory neurotransmitter and neurotoxin, occurs in human AMD. MATERIALS AND METHODS: We examined 40 subjects, 18 of whom were AMD, abstinent more than 3 weeks and 22 were age matched controls.

Evaluation of three different protocols of protein extraction for Arabidopsis thaliana leaf proteome analysis by two-dimensional electrophoresis.

This work was performed to compare three precipitation protocols of protein extraction for 2-DE proteomic analysis using Arabidopsis leaf tissue: TCA-acetone, phenol, and TCA-acetone-phenol. There were no statistically significant differences in protein yield between the three methods. Samples were subjected to 2-DE in the 5 to 8 pH and 14-80 kDa ranges.

Plant cysteine proteinases: evaluation of the pharmacological activity.

Cysteine proteinases are involved in virtually every aspect of plant physiology and development. They play a role in development, senescence, programmed cell death, storage and mobilization of germinal proteins, and in response to various types of environmental stress. In this review, we focus on a group of plant defensive enzymes occurring in germinal tissue of Caricaceae.

In vivo antitumoral activity of stem pineapple (Ananas comosus) bromelain.

Stem bromelain (EC 3.4.22.

[Mycophenolate mofetil in lupus nephritis refractory to intravenous cyclophosphamide].

Objective: To evaluate the use of mycophenolate mofetil (MMF) in lupus nephritis (LN) patients with prior failure to intravenous cyclophosphamide over a 12-month follow-up.

Patients And Methods: Eleven patients with LN were included. MMF doses ranged from 1.

[Congenital percutaneous aortic valvuloplasty in 70 subjects with congenital aortic stenosis, mid-term results].

Objective: To evaluate mid-term results with Percutaneous aortic valvuloplasty (PAV).

Material And Methods: Records of 70 patients treated with percutaneous aortic valvuloplasty with at least 6 months follow-up were reviewed.

Results: The 70 patients with PAV aged 3 months to 36 years, mean 10.

Tricuspid atresia associated with common arterial trunk and 22q11 chromosome deletion.

The case of a four-months old male with coexistent tricuspid atresia and common arterial trunk is presented. The diagnosis was made by cardiac catheterization and selective angiocardiography. Clinical considerations are discussed and the review of the available literature reveals this patient to be the tenth case reported of this very unusual association of cardiovascular defects, and the first with positive deletion of the 22q11 chromosome.