Publications by authors named "Martha H Uribe Ramos"

Background: Transient elastography is a noninvasive method for the evaluation of fibrosis in chronic liver disease. However, its reliability is variable, and the factors associated with its accuracy have not been identified completely.

Aims: To identify the factors associated with the reliability of transient elastography.

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The prevalence of non-alcoholic steatohepatitis has increased in the last years, paralleling the increasing incidence of overweight and obesity in the general population and related comorbidities. It is expected that in near future, non-alcoholic steatohepatitis will be responsible for a large number of subjects with chronic liver disease due to fatty liver Because of this, treatment options for fatty liver are necessary. To date, the cornerstone of treatment is based in weight reduction, with diet and increased physical activity, although reports indicating that insulin sensitizers and medications that reduce oxidative stress may hold promise for the treatment of this condition.

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Article Synopsis
  • The study investigated the prevalence of hepatitis B (HBV) and hepatitis C (HCV) infections among nurses at Medica Sur Clinic in Mexico, given their high risk of exposure.
  • Among 376 nurses, 1.6% tested positive for HBV exposure (Anti-HBc), but no one was actively infected (HBsAg positive), while 0.8% were positive for HCV antibodies, indicating prior exposure.
  • Risk factors identified included having tattoos and multiple sexual partners for HBV, and older transfusions for HCV, with one nurse showing a significant viral load and HCV genotype 2b, but overall seropositivity was lower than in the general population.
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Objective: Investigate the association between polymorphisms in the leptin receptor gene associated with obesity and gallstone disease.

Design: We conducted a cross-sectional study, carried out at a tertiary setting.

Subjects: We enrolled 97 subjects, comprising 54 subjects with gallstones (cases) and 43 controls (without gallstones).

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Article Synopsis
  • - The study aimed to investigate how ghrelin, a hormone, might influence the development of gallstone disease by comparing 38 patients with gallstones to 112 healthy controls.
  • - Results indicated significant differences between the two groups regarding age, body mass index (BMI), and other metabolic factors, with higher ghrelin levels linked to a lower risk of gallstone disease.
  • - Overall, findings suggest that higher serum ghrelin concentrations could provide a protective effect against gallstones, as evidenced by a notable presence of ghrelin mRNA in gallbladder samples.
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