Gender effect of glucose, insulin/glucagon ratio, lipids, and nitrogen-metabolites on serum HGF and EGF levels in patients with diabetes type 2.

Hepatocyte growth factor (HGF) exhibits potent growth-inducing properties across various tissues, while epidermal growth factor (EGF) acts as a molecular integration point for diverse stimuli. HGF plays a crucial role in hepatic metabolism, tissue repair, and offers protective effects on epithelial and non-epithelial organs, in addition to its involvement in reducing apoptosis and inflammation, underscoring its anti-inflammatory capabilities. The HGF-Met system is instrumental in hepatic metabolism and enhancing insulin sensitivity in animal diabetes models.

Intervention strategies with 2D cellular automata for testing SARS-CoV-2 and reopening the economy.

During the period of time between a new disease outbreaks and its vaccine is deployed, the health and the economic systems have to find a testing strategy for reopening activities. In particular, asymptomatic individuals, who transmit locally the COVID-19 indoors, have to be identified and isolated. We proposed a 2D cellular automaton based on the SI epidemic model for selecting the most desirable testing frequency and identifying the best fitting size of random trails on local urban environments to diagnose SARS-CoV-2 and isolate infected people.

Horseback riding pathways and harbors at the beginning of the colonial era in Mexico.

The introduction of horses in the New World changed the way of traveling on complex terrains. This change reconfigured the land transport network connecting harbors in the region. However, data of horseback riding pathways among harbors is scarce.

The role of oxidant stress and gender in the erythrocyte arginine metabolism and ammonia management in patients with type 2 diabetes.

Objectives: To study the differences in the levels of nitrogen metabolites, such as ammonia and nitric oxide and the correlations existing among them in both red blood cells (RBCs) and serum, as well as the possible differences by gender in healthy subjects and patients with type 2 Diabetes Mellitus (DM).

Design And Methods: This cross-sectional study included 80 patients diagnosed with type 2 DM (40 female and 40 male patients) and their corresponding controls paired by gender (40 female and 40 male). We separated serum and RBC and determined metabolites mainly through colorimetric and spectrophotometric assays.

Nonlinearity and distance of ancient routes in the Aztec Empire.

This study explores the way in which traveling paths in ancient cultures are characterized by the relationship between nonlinear shapes and path lengths in terms of distances. In particular, we analyze the case of trade routes that connected Aztec settlements around 1521 CE in central Mexico. Based on the complex systems perspective, we used the least cost path approximation to reconstruct a hypothetical large-scale map of routes reproducing physical connections among ancient places.

Propagation of economic shocks in input-output networks: a cross-country analysis.

This paper investigates how economic shocks propagate and amplify through the input-output network connecting industrial sectors in developed economies. We study alternative models of diffusion on networks and we calibrate them using input-output data on real-world inter-sectoral dependencies for several European countries before the Great Depression. We show that the impact of economic shocks strongly depends on the nature of the shock and country size.