An in vitro study of fluoride-preloaded halloysite nanotubes to enhance the fluoride release in conventional and resin-modified glass ionomer cements.

Objective: The purpose of the study was to compare the fluoride release in two conventional glass ionomer cements (Ionobond, Ketac Molar) and two resin-modified glass ionomer cements (Vitrebond, Fuji II LC) adapted with halloysite nanotubes preloaded with sodium fluoride at different concentrations.

Methods: In total, 96 samples were prepared and distributed into four control groups and eight experimental groups (5 % and 10 %). Totals of 10 % and 5 % of the total weight of ionomer powder needed to prepare the samples were replaced with nanotubes, preloaded at 2,000 parts per million, respectively.