Development of a Novel Soft Tissue Measurement Device for Individualized Finite Element Modeling in Custom-Fit CPAP Mask Evaluation.

Purpose: Individual facial soft tissue properties are necessary for creating individualized finite element (FE) models to evaluate medical devices such as continuous positive airway pressure (CPAP) masks. There are no standard tools available to measure facial soft tissue elastic moduli, and techniques in literature require advanced equipment or custom parts to replicate.

Methods: We propose a simple and inexpensive soft tissue measurement (STM) indenter device to estimate facial soft tissue elasticity at five sites: chin, cheek near lip, below cheekbone, cheekbone, and cheek.

Moldable Mask: A Reusable, Hot Water Moldable, Additively Manufactured Mask to Be Used as an N95 Alternative.

There has been high demand for personal protective equipment (PPE) during the COVID-19 pandemic, especially N95 respirators. Unfortunately, at the early stage of the pandemic, the supply could not meet the demand for N95 respirators, leading to a shortage and unsafe reuse of this form of PPE. We developed the Moldable Mask to ease the demand for N95 respirators by creating a 3D-printed mask that uses a piece of N95 material as a filter.

Partial purification of parathyrin from the corpuscles of Stannius (PCS) of the eel (Anguilla anguilla, L.).

It has been previously shown that the eel corpuscles of Stannius (CS) synthesize and secrete a substance (PCS) which is functionally and immunologically related to the mammalian parathyrin family. Purification of PCS, including anion-exchange chromatography, ODS C-18 reverse-phase HPLC, and affinity chromatography, showed that a biologically active peak, eluted in 32% acetonitrile, contains a 32- to 34-kDa protein which is 600-fold more potent than the crude extract is a test involving the hypocalcemic response in the CS-deprived eel. Specific immunoprecipitation of protein encoded by mRNA extracted from eel CS indicates that a 45-kDa precursor is involved in PCS synthesis.

Calcium-dependent metabolism of 25-hydroxycholecalciferol in silver eel tissues.

We investigated the in vitro metabolism of [26,27-3H]-25-(OH)D3 in different eel tissues. After incubation with [3H]-25-(OH)D3, tissues were extracted with methanol-chloroform and chromatographed on Sephadex LH 20 columns. Two derivatives less polar than 25-(OH)D3 were detected, the first one being sensitive to KOH treatment.

[In vitro translation of RNA extracted from corpuscules of Stannius of the eel (Anguilla anguilla); identification of the precursor of parathyrin in the corpuscules of Stannius (PCS)].

Corpuscles of Stannius (CS) of Teleosts secrete a PTH like hormone (Parathyrin of CS: PCS) which is involved in calcium metabolism by acting mainly at the gill level. Translated products encoded by mRNA extracted from Eel Corpuscles of Stannius and among these, translated products immunoprecipitated by anti b-PTH immunserum were compared to the products synthetized during incubation of the glands with labelled methionine. The analysis was performed by polyacrylamide gel electrophoresis and fluorography.

[Comparative effects of an extract of Anguilla Stannius corpuscles and of an active fragment of human parathyroid hormone (1-34 hPTH) on an anuran batracian, Xenopus laevis].

Parathyrin of the corpuscles of Stannius (PCS), glands which are restricted to Holostei and Teleostei, resembles mammalian parathyroid hormone secreted by the parathyroids. These glands made their first phylogenic appearance with Amphibians, whereas the Stannius corpuscles disappeared. We have compared, in the clawed toad, Xenopus laevis, the effects of injections of extracts of corpuscles of Stannius and of the active synthetic fragment of parathyrin (1-34 hPTH).

[Effect of salmon calcitonin on intestinal absorption of calcium in the eel (Anguilla anguilla L.)].

Salmon calcitonin (SCT) acted, in eel, on Ca intestinal absorption by modulating Ca flux lumen-plasma (phi Calp) intensity. This response was dependent upon the basal value of the intestinal Ca absorption; a linear relation between the basal phi Calp and its variation after SCT was shown. After Stannius corpuscles removal the lower phi Calp was stimulated by SCT in all cases.

[Structural similarities between the hypocalcemia hormone of the corpuscles of Stannius of the eel (Anguilla anguilla L.) and the mammalian parathyroid hormone].

Extracts of the corpuscules of Stannius enhance Eel gill calcium efflux and increase bone resorption in the Rat. Thus the hormone is hypocalcaemic in the Eel although hypercalcaemic in the Rat. We show here that a 15 min.

Paradoxical effect of 1,25 dihydroxycholecalciferol on osteoblastic and osteoclastic activity in the skeleton of the eel Anguilla anguilla L.

Female mature eels (300 to 500 g) received one intraperitoneal injection of 1.25(OH)2D3 (10 microgram). Their vertebral bone was compared, 8 h and 24 h after the injection, with vertebral bone of control mature female eels receiving solvent alone (ethanol).

[Morphological, cytological, and biochemical changes of Anguilla anguilla L. gills deprived of Stannius corpuscles (S. C.) (author's transl)].

In the silver female eel (Anguilla anguilla L.) maintained in fresh water, surgical removal of Stannius corpuscles (SC) resulted in: a) A significant increase of wet weight of gill cells and the dry weight of gill filaments expressed as function of body weight. b) A proliferation and a hypertrophy of chloride cells shown by a significant rise of cell volume expressed as a precentage of the epithelial volume.

Effects of calcitonin and ultimobranchialectomy (UBX) on calcium and bone metabolism in the eel, Anguilla anguilla L.

Prolonged administration of synthetic salmon calcitonin (SCT) to immature female silver eels, maintained in sea water, provoked a decrease of the serum calcium concentration and an increase of both the osteoblastic apposition and of the degree of mineralization of the intercellular matrix in the vertebral bone. The osteoclastic resorption and osteocytic osteolysis were not significantly affected, however the osteoclastic index was reduced. The ultimobranchial body, site of CT secretion, was cauterized in immature female silver eels maintained in Ca++ rich tap water.