Publications by authors named "Martel C"

Background: Despite evidence demonstrating that influenza vaccination is associated with reduced risk of cardiovascular events and all-cause mortality in individuals with diabetes mellitus (DM), vaccine uptake remains suboptimal.

Objectives: The purpose of this study was to assess the effectiveness of electronically delivered nudges on influenza vaccine uptake according to the presence of DM status versus other chronic diseases.

Methods: NUDGE-FLU-CHRONIC was a nationwide, randomized, pragmatic implementation trial among younger and middle-aged (18-64 years) Danish citizens with chronic disease during the 2023/2024 influenza season.

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  • The study focuses on the significance of influenza vaccination in patients with acute myocardial infarction (AMI) and evaluates methods to enhance vaccine uptake among this high-risk group.
  • The research consists of three nationwide randomized clinical trials conducted in Denmark that tested the effectiveness of electronically delivered behavioral nudges against usual care in increasing vaccination rates among AMI patients.
  • The primary outcome measured was the rate of influenza vaccinations received, with findings suggesting that these behavioral nudges could potentially improve vaccination uptake in the targeted population.
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  • Individuals are more likely to connect with people who share their political views (copartisans) rather than those with opposing views (counter-partisans) on social media.
  • A Twitter field experiment showed that users were more inclined to follow back accounts labeled as human and associated with their political party compared to those identified as bots or from the opposing party.
  • Additional survey results indicated that factors like issue polarization, dislike for opposing parties, and fondness for one's own party influenced users' decisions to reciprocate connections online.
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  • Despite strong guidelines, flu vaccination rates are low among young and middle-aged people with chronic illnesses, indicating a need for effective strategies to boost these rates.
  • A nationwide clinical trial in Denmark tested whether sending behaviorally informed electronic letters could increase flu vaccination uptake in patients aged 18 to 64 with chronic diseases.
  • Results showed that patients who received any intervention letters had a higher vaccination rate (39.6%) compared to those who received usual care (27.9%), with the most significant impact coming from a follow-up letter sent 10 days later.
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Myxozoa is a class of the Phylum Cnidaria made up of endoparasites from aquatic habitats. The genus Ceratomyxa preferentially infects marine fish, with the gallbladder being the main site parasitized. This study aimed to describe a new species of Ceratomyxa found in this organ in Boulengerella cuvieri using morphological, morphometric characterization and phylogenetic analysis of 18S rDNA gene sequences.

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Hypertrophic scarring is a common complication in severely burned patients who undergo autologous skin grafting. Meshed skin grafts tend to contract during wound healing, increasing the risk of pathological scarring. Although various technologies have been used to study cellular contraction, current methods for measuring contractile forces at the tissue level are limited and do not replicate the complexity of native tissues.

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Lipid metabolism is recognised as being central to growth, disease and health. Lipids, therefore, have an important place in current research on globally significant topics such as food security and biodiversity loss. However, answering questions in these important fields of research requires not only identification and measurement of lipids in a wider variety of sample types than ever before, but also hypothesis-driven analysis of the resulting 'big data'.

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Background: Maternally-inherited symbionts can induce pre-mating and/or post-mating reproductive isolation between sympatric host lineages, and speciation, by modifying host reproductive phenotypes. The large parasitoid wasp genus Cotesia (Braconidae) includes a diversity of cryptic species, each specialized in parasitizing one to few related Lepidoptera host species. Here, we characterized the infection status of an assemblage of 21 Cotesia species from 15 countries by several microbial symbionts, as a first step toward investigating whether symbionts may provide a barrier to gene flow between these parasitoid host lineages.

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Warning labels from professional fact-checkers are one of the most widely used interventions against online misinformation. But are fact-checker warning labels effective for those who distrust fact-checkers? Here, in a first correlational study (N = 1,000), we validate a measure of trust in fact-checkers. Next, we conduct meta-analyses across 21 experiments (total N = 14,133) in which participants evaluated true and false news posts and were randomized to either see no warning labels or to see warning labels on a high proportion of the false posts.

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Background: Allergen-carrying virus-like particles are effective and safe means of allergen immunotherapy (AIT) in rodent models.

Objective: To study the development of allergen-blocking immunoglobulin (Ig)G in dogs injected with Der f 2-carrying enveloped plant-based bioparticles (eBPs).

Materials And Methods: Laboratory beagle dogs were injected intradermally (ID) or subcutaneously (SC) with Der f 2-eBP three times at 2-week intervals.

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  • Digital letter interventions effectively increased influenza vaccination rates among Danish citizens aged 65 and older during the 2023-2024 flu season through a randomized trial.
  • Participants were divided into groups receiving usual care or various behaviorally informed electronic nudges before vaccination, revealing higher rates of vaccination in the nudge group compared to usual care (76.32% vs. 76.02%).
  • The nudges helped particularly those who were unvaccinated in the previous season, with consistent effects observed across different years, highlighting their scalability and potential for future flu seasons.
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Lymphatic vessels are essential for preventing the accumulation of harmful components within peripheral tissues, including the artery wall. Various endogenous mechanisms maintain adequate lymphatic function throughout life, with platelets being essential for preserving lymphatic vessel integrity. However, since lymph lacks platelets, their impact on the lymphatic system has long been viewed as restricted to areas where lymphatics intersect with blood vessels.

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Despite the major roles of choroid plexus epithelial cells (CPECs) in brain homeostasis and repair, their developmental lineage and diversity remain undefined. In simplified differentiations from human pluripotent stem cells, derived CPECs (dCPECs) displayed canonical properties and dynamic multiciliated phenotypes that interacted with Aβ uptake. Single dCPEC transcriptomes over time correlated well with human organoid and fetal CPECs, while pseudotemporal and cell cycle analyses highlighted the direct CPEC origin from neuroepithelial cells.

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Land-use change is one the greatest threats to biodiversity and is projected to increase in magnitude in the coming years, stressing the importance of better understanding how land-use change may affect vital ecosystem services, such as pollination. Past studies on the impact of land-use change have largely focused on only one aspect of the pollination process (e.g.

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There is strong political assortment of Americans on social media networks. This is typically attributed to preferential tie formation (i.e.

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Drug-induced liver injury (DILI) represents a major issue for pharmaceutical companies, being a potential cause of black-box warnings on marketed pharmaceuticals, or drug withdrawal from the market. Lipid accumulation in the liver also referred to as steatosis, may be secondary to impaired mitochondrial fatty acid oxidation (mtFAO). However, an overall causal relationship between drug-induced mtFAO inhibition and the occurrence of steatosis in patients has not yet been established with a high number of pharmaceuticals.

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  • Lean patients with NAFLD can experience cardiac issues without already having metabolic problems or obesity.
  • Researchers studied mice with liver mitochondrial deficiencies, which develop liver fat but not obesity, to understand this connection.
  • The findings revealed that male mice showed more significant cardiac dysfunction and metabolic disturbances than female mice, who had different cardiometabolic problems involving liver and cardiac lipid imbalances.
  • This research highlights how liver metabolism can lead to cardiac issues differently in males and females, emphasizing the need to explore these gender-related differences further in lean NAFLD.
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The spread of misinformation is a pressing societal challenge. Prior work shows that shifting attention to accuracy increases the quality of people's news-sharing decisions. However, researchers disagree on whether accuracy-prompt interventions work for U.

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Background: In the NUDGE-FLU (Nationwide Utilization of Danish Government Electronic letter system for increasing inFLUenza vaccine uptake) trial, electronic letters incorporating cardiovascular (CV) gain-framing and repeated messaging increased influenza vaccination by approximately 1 percentage point.

Objective: To evaluate the effects of the successful nudging interventions on downstream clinical outcomes.

Design: Prespecified exploratory analysis of a nationwide randomized implementation trial.

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Background: Yearly influenza vaccination is strongly recommended for older adults and patients with chronic diseases including cardiovascular disease (CVD); however, vaccination rates remain suboptimal, particularly among younger patients. Electronic letters incorporating behavioral nudges are highly scalable public health interventions which can potentially increase vaccination, but further research is needed to determine the most effective strategies and to assess effectiveness across different populations. The purpose of NUDGE-FLU-CHRONIC and NUDGE-FLU-2 are to evaluate the effectiveness of electronic nudges delivered via the Danish governmental electronic letter system in increasing influenza vaccination among patients with chronic diseases and older adults, respectively.

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Angiopoietin-like 2 (ANGPTL2) is a pro-inflammatory and pro-oxidant circulating protein that predicts and promotes chronic inflammatory diseases such as atherosclerosis in humans. Transgenic murine models demonstrated the deleterious role of ANGPTL2 in vascular diseases, while deletion of ANGPTL2 was protective. The nature of its role in cardiac tissues is, however, less clear.

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We present adult normalized data for MindPulse (MP), a new tool evaluating attentional and executive functioning (AEF) in decision-making. We recruited 722 neurotypical participants (18-80 years), with 149 retested. The MP test includes three tasks: Simple Reaction Time (SRT), Go/No-go, and complex Go/No-go, involving perceptual components, motor responses, and measurements of reaction time (RT) and correctness.

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