Publications by authors named "Marta X Leon"

Article Synopsis
  • Patients with end-stage renal disease often experience painful muscle cramps during dialysis, and there are currently limited effective and safe treatments available.
  • The systematic review included 13 studies on various pharmacological interventions to alleviate these muscle cramps, with vitamin C and E showing the most favorable results, while L-carnitine emerged as a promising option for further research.
  • The review emphasizes the need for high-quality future studies that consider patient experiences and use well-defined samples to enhance treatment approaches.
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Objectives: Due to the increase in the prevalence of non-communicable diseases and the Colombian demographic transition, the necessity of palliative care has arisen. This study used accessibility and coverage indicators to measure the geographic barriers to palliative care.

Methods: Population-based observational study focused on urban areas and adult population from Colombia, which uses three measurements of geographic accessibility to services: a) density of palliative care services per 100,000 inhabitants, b) analysis of geographic distribution by territorial nodes of the country, and c) spatial analysis of palliative care services using Voronoi diagrams.

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Patients with life-limiting illnesses receiving palliative care have a high symptom burden that can be challenging to manage. Guided imagery (GI), a complementary and integrative therapy in which patients are induced to picture mental images with sensory components, has proven in quasi-experimental studies to be effective as a complementary therapy for symptom management. To systematically review randomized controlled trials that report evidence of guided imagery for symptom management in patients with life-limiting illnesses.

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Patients requiring home-based palliative care have advanced complex illnesses with functional limitations and decline. This retrospective study reviewed caregiver administration of subcutaneous (SQ) medications and fluids when symptom control could not be achieved using the oral route. Medical records from September 1, 2017 to February 28, 2018 were reviewed for 272 consecutive patients who received SQ administration of medications or fluids at a home-based palliative care program.

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Article Synopsis
  • The study evaluates the regional development of palliative care in Colombia using international indicators to identify gaps and improvements.
  • Approximately 41% of people in Colombia who die require palliative care, yet the average availability of specialized services is extremely low at 0.5 per 100,000 inhabitants.
  • Findings reveal significant disparities in palliative care access across 33 regions, highlighting particularly poor services in rural areas compared to regions with higher integration of palliative care services.
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Non-communicable diseases, including cancer, are overtaking infectious disease as the leading health-care threat in middle-income and low-income countries. Latin American and Caribbean countries are struggling to respond to increasing morbidity and death from advanced disease. Health ministries and health-care systems in these countries face many challenges caring for patients with advanced cancer: inadequate funding; inequitable distribution of resources and services; inadequate numbers, training, and distribution of health-care personnel and equipment; lack of adequate care for many populations based on socioeconomic, geographic, ethnic, and other factors; and current systems geared toward the needs of wealthy, urban minorities at a cost to the entire population.

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Opioid analgesics are simultaneously indispensable medicines for the treatment of moderate to severe pain and are harmful when abused. The challenge for governments is to balance the obligation to prevent diversion, trafficking, and abuse of opioids with the equally important obligation to ensure their availability and accessibility for the relief of pain and suffering. Over the last 30 years, significant progress has been made toward improving access to opioids as measured by increasing global medical opioid consumption.

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Latin America consumes less than 2.7% of the morphine in the world, as reported by the governments to the International Narcotics Control Board. Methods to improve access to opioids for the treatment of pain have been developed by the Pain & Policy Studies Group (PPSG), a World Health Organization Collaborating Center at the University of Wisconsin.

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