How to Promote Skin Repair? In-Depth Look at Pharmaceutical and Cosmetic Strategies.

Skin repair encompasses epidermal barrier repair and wound healing which involves multiple cellular and molecular stages. Therefore, many skin repair strategies have been proposed. In order to characterize the usage frequency of skin repair ingredients in cosmetics, medicines, and medical devices, commercialized in Portuguese pharmacies and parapharmacies, a comprehensive analysis of the products' composition was performed.

Real-Time Measurement of Refractive Index Using 3D-Printed Optofluidic Fiber Sensor.

This work describes a 3D-printed optofluidic fiber sensor to measure refractive index in real time, combining a microfluidic system with an optical fiber extrinsic Fabry-Perot interferometer. The microfluidic chip platform was developed for this purpose through 3D printing. The Fabry-Perot cavity was incorporated in the microfluidic chip perpendicularly to the sample flow, which was of approximately 3.

Hybrid sensor based on a hollow square core fiber for temperature independent refractive index detection.

In this work, a hybrid sensor based on a section of hollow square core fiber (HSCF) spliced between two single mode fibers is proposed for the measurement of refractive index of liquids. The sensor, with a length of a few millimeters, operates in a transmission configuration. Due to the HSCF inner geometry, two different interferometers are generated.

Simultaneous measurement of displacement and temperature using a balloon-like hybrid fiber sensor.

A fiber sensor based on a silica capillary in a balloon-like shape for simultaneous measurement of displacement and temperature is proposed and experimentally demonstrated. The sensor is fabricated by splicing a segment of a hollow-core fiber between two single-mode fibers (SMF) and by creating a balloon shape with the capillary at the top-center position. The SMF-capillary-SMF configuration excites an antiresonant (AR) guidance, and the balloon shape enhances the Mach-Zehnder interferometer (MZI).

Optical Fiber Sensor for Monitoring the Evaporation of Ethanol-Water Mixtures.

An inline optical fiber sensor is proposed to monitor in real time the evaporation process of ethanol-water binary mixtures. The sensor presents two interferometers, a cladding modal interferometer (CMI) and a Mach-Zehnder interferometer (MZI). The CMI is used to acquire the variations in the external medium refractive index, presenting a maximum sensitivity of 387 nm/RIU, and to attain the variation in the sample concentration profile, while the MZI monitors temperature fluctuations.

Double Antiresonance Fiber Sensor for the Simultaneous Measurement of Curvature and Temperature.

Antiresonant hollow core fibers (ARHCFs) have gained some attention due to their notoriously attractive characteristics on managing optical properties. In this work, an inline optical fiber sensor based on a hollow square core fiber (HSCF) is proposed. The sensor presents double antiresonance (AR), namely an internal AR and an external AR.

Sensitive skin: Active ingredients on the spotlight.

Objective: Sensitive skin is characterized by self-reported sensory perceptions in response to stimuli that should not provoke unpleasant sensations. Cosmetic products for sensitive skin are designed to minimize these symptoms. This study aimed to unveil the most used active ingredients for sensitive skin in facial care products from the pharmacy and parapharmacy channel.

Usage of Synthetic Peptides in Cosmetics for Sensitive Skin.

Sensitive skin is characterized by symptoms of discomfort when exposed to environmental factors. Peptides are used in cosmetics for sensitive skin and stand out as active ingredients for their ability to interact with skin cells by multiple mechanisms, high potency at low dosage and the ability to penetrate the stratum corneum. This study aimed to analyze the composition of 88 facial cosmetics for sensitive skin from multinational brands regarding usage of peptides, reviewing their synthetic pathways and the scientific evidence that supports their efficacy.

Marine Ingredients for Sensitive Skin: Market Overview.

Marine ingredients are a source of new chemical entities with biological action, which is the reason why they have gained relevance in the cosmetic industry. The facial care category is the most relevant in this industry, and within it, the sensitive skin segment occupies a prominent position. This work analyzed the use of marine ingredients in 88 facial cosmetics for sensitive skin from multinational brands, as well as their composition and the scientific evidence that supports their efficacy.

Trends in the Use of Botanicals in Anti-Aging Cosmetics.

Botanical ingredients have been used for thousands of years in skincare for their convenience as well as the diversity and abundance in compounds with biological activity. Among these, polyphenols and especially flavonoids have gained increasing prominence due to their antioxidant and anti-inflammatory properties. In this study, the most used botanical preparations in anti-aging products marketed in 2011 were determined.

Negative curvature hollow core fiber sensor for the measurement of strain and temperature.

Three different types of strain and temperature sensors based on negative curvature hollow core fiber (NCHCF) are proposed. Each sensor is produced by splicing a small section of the NCHCF between two sections of single mode fiber. Different types of interferometers are obtained simply by changing the splicing conditions.

Optical Harmonic Vernier Effect: A New Tool for High Performance Interferometric Fibre Sensors.

The optical Vernier effect magnifies the sensing capabilities of an interferometer, allowing for unprecedented sensitivities and resolutions to be achieved. Just like a caliper uses two different scales to achieve higher resolution measurements, the optical Vernier effect is based on the overlap in the responses of two interferometers with slightly detuned interference signals. Here, we present a novel approach in detail, which introduces optical harmonics to the Vernier effect through Fabry-Perot interferometers, where the two interferometers can have very different frequencies in the interferometric pattern.

Fabry-Perot cavity based on silica tube for strain sensing at high temperatures.

In this work, a Fabry-Perot cavity based on a new silica tube design is proposed. The tube presents a cladding with a thickness of ~14 μm and a hollow core. The presence of four small rods, of ~20 μm diameter each, placed in diametrically opposite positions ensure the mechanical stability of the tube.

Silica microspheres array strain sensor.

An optical fiber sensor based on arrays of silica microspheres is proposed. The microspheres are produced separately using a fusion splicer and then also connected in series by fusion splicing. Three different sensors are presented, differing by the number of microspheres.

Towards the control of highly sensitive Fabry-Pérot strain sensor based on hollow-core ring photonic crystal fiber.

A high sensitivity Fabry-Pérot (FP) strain sensor based on hollow-core ring photonic crystal fiber was investigated. A low-finesse FP cavity was fabricated by splicing a section of hollow-core ring photonic crystal fiber between two standard single mode fibers. The geometry presents a low cross section area of silica enabling to achieve high strain sensitivity.

Spatial optical filter sensor based on hollow-core silica tube.

A spatial optical filter based on a hollow-core silica tube is proposed. Because of the hollow-core dimensions, it is possible to obtain a periodical spatial filter ranging from 1200 to 1700 nm with a channel spacing of 2.64 THz.

Fabry-Perot cavity based on a diaphragm-free hollow-core silica tube.

A Fabry-Perot (FP) cavity of simple design and based on a pure silica diaphragm-free hollow tube is proposed. Its operation is based on a first reflection of light at the end of the single-mode fiber that illuminates the silica rod and in a second reflection that takes place at the end of the rod. The FP cavity is characterized for high temperature, pressure and refractive index sensing, showing useful characteristics for the measurement of these three parameters.

[Analysis of the patient safety culture in hospitals of the Spanish National Health System].

Background And Objectives: A safety culture is essential to minimize errors and adverse events. Its measurement is needed to design activities in order to improve it. This paper describes the methods and main results of a study on safety climate in a nation-wide representative sample of public hospitals of the Spanish NHS.