Publications by authors named "Marta R Orejuela"

Article Synopsis
  • The role of alternative splicing (AS) in stem cells is not well understood, especially compared to transcriptional regulation.
  • Researchers studied AS in planarian stem cells and found a conserved program that includes many different alternative exons and introns, revealing key regulators of this process.
  • The interaction between CELF and MBNL proteins is crucial for regulating stem cell-specific AS, and altering these factors affects the stem cells’ ability to regenerate and differentiate.
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Circular RNAs (circRNAs) are a large class of animal RNAs. To investigate possible circRNA functions, it is important to understand circRNA biogenesis. Besides human ALU repeats, sequence features that promote exon circularization are largely unknown.

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Odorant-binding proteins (OBPs) and chemosensory proteins (CSPs) are small soluble polypeptides that bind semiochemicals in the lymph of insect chemosensilla. In the genome of Anopheles gambiae, 66 genes encode OBPs and 8 encode CSPs. Here we monitored their expression through classical proteomics (2D gel-MS analysis) and a shotgun approach.

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