Comprehensive toxicological multi-year study on pesticides in apples: Control, trends and dietary risk assessment.

Apples are one of the most widely consumed raw fruit worldwide. Due to multiple sprayings during the growing season, they can contain pesticide residues affecting quality of food and human health. The novelty of the present study was a comprehensive multi-year control of a broad spectrum of pesticides in apples (2006-2022) and dietary risk assessment with changing toxicological values: ADI/ARfD/MRL.

Chlorpyrifos Occurrence and Toxicological Risk Assessment: A Review.

Chlorpyrifos (CPF) was the most frequently used pesticide in food production in the European Union (EU) until 2020. Unfortunately, this compound is still being applied in other parts of the world. National monitoring of pesticides conducted in various countries indicates the presence of CPF in soil, food, and water, which may have toxic effects on consumers, farmers, and animal health.

Ophthalmic manifestations of atopic dermatitis.

Atopic dermatitis is a chronic condition of complex etiology, whose clinical course involves remission and recurrence. It is not an isolated disease entity affecting only the skin, but one that co-occurs with disorders of other organs. Numerous literature reports have long confirmed the relationship between the disorder and a growing number of ophthalmic manifestations such as keratoconus and retinal detachment.

[The opinion of the Expert Group of the Polish Society of Ophthalmology on using nepafenac in the prevention of postoperative macular edema after cataract surgery in diabetic patients].

Nepafenac is an innovative non-steroidal anti-inflammatory drug used in ophthalmology for the prevention of macular edema after cataract surgery. Along with its anti-inflammatory effect, nepafenac has some unique properties which distinguish it from other non-steroidal anti-inflammatory drugs. It is a prodrug activated to amfenac after it penetrates through the corneal layers to the aqueous humour and the ciliary body.