Publications by authors named "Marta Pena-Gonzalez"
Alzheimers Dement
September 2024
Article Synopsis
- Early-onset Alzheimer's disease (EOAD) has more severe neuropsychiatric symptoms and lower integrity of the locus coeruleus (LC) compared to late-onset Alzheimer's disease (LOAD).
- A study involving 104 subjects with AD and 32 healthy controls used MRI and other measurements to analyze the differences in LC integrity and symptoms between EOAD and LOAD.
- Results showed that EOAD's lower LC integrity correlates with increased neuropsychiatric symptoms, and its greater degeneration may explain these severe symptoms compared to LOAD.
