Supramolecular Subphthalocyanine Cage as Catalytic Container for the Functionalization of Fullerenes in Water.

Herein we report the first example of a supramolecular cage that works as a catalytic molecular reactor to perform transformations over fullerenes in aqueous medium. Taking advantage of the ability of metallo-organic Pd(II)-subphthalocyanine (SubPc) capsules to form stable host:guest complexes with C , we have prepared a water-soluble cage that provides a hydrophobic environment for conducting cycloadditions over encapsulated C , namely, Diels-Alder reactions with anthracene. Indeed, the presence of catalytic amounts of SubPc cage dissolved in water promotes co-encapsulation of insoluble C and anthracene substrates, allowing the reaction to occur inside the cavity under mild conditions.

Glycosylated BODIPY- Incorporated Pt(II) Metallacycles for Targeted and Synergistic Chemo-Photodynamic Therapy.

Pt(II)-BODIPY complexes combine the chemotherapeutic activity of Pt(II) with the photocytotoxicity of BODIPYs. Additional conjugation with targeting ligands can boost the uptake by cancer cells that overexpress the corresponding receptors. We describe two Pt(II) triangles, and , built with pyridyl BODIPYs functionalized with glucose () or triethylene glycol methyl ether (), respectively.

Subphthalocyanine capsules: molecular reactors for photoredox transformations of fullerenes.

The internal cavity formed by a dimeric subphthalocyanine (SubPc) capsule (SubPcPd, 2), ensembled by coordination of pyridyl substituents in the monomeric SubPc 1 to Pd centers, has proved an optimal space for the complexation of C fullerene. Taking advantage of the intense absorption of green light of the SubPc component at around 550 nm, we have tested different green-light induced photoredox addition reactions over the double bonds of guest C. Both addition of amine radicals, generated by reductive quenching of the excited state of 2 by aromatic trimethylsilylamines, and addition of trifluoroethyl radicals, obtained from oxidative quenching of the photosensitizer, have successfully taken place with good yields in the 2:C host:guest complex.