Phytochemical characterization, toxicity and pharmacological profile of the central effects of the fixed fruit pulp oil of Mauritia flexuosa L.F. (buriti).

Anxiety and depression are mental disorders that have been exponentially increasing over the last decades. Psychopharmacology emerged to try to alleviate the symptoms of these disorders; however, the side effects and the time it takes to achieve the desired effect are factors that decrease the search for and adherence to treatment. To remedy this situation, new compounds capable of improving the performance of these medications and reducing their adverse effects have been sought.

[The Psychoactive Power of Foods: A Case of Acute Nutmeg Intoxication].

Ingestion of high doses of nutmeg causes potentially serious and disabling medical and psychiatric consequences. No isolated component of nutmeg has been identified as responsible for all symptoms observed during intoxication, however myristicin, one of the essential oil's components of this spice, is believed to be responsible for most psychoactive effects, although the exact mechanism is not known. Other constituents, such as elemicin, may also be involved.

Corpus Callosum and Neglect Syndrome: Clinical Findings After Meningioma Removal and Anatomical Review.

Two types of neglect are described: hemispatial and motivational neglect syndromes. Neglect syndrome is a neurophysiologic condition characterized by a malfunction in one hemisphere of the brain, resulting in contralateral hemispatial neglect in the absence of sensory loss and the right parietal lobe lesion being the most common anatomical site leading to it. In motivational neglect, the less emotional input is considered from the neglected side where anterior cingulate cortex harbors the most frequent lesions.

[Bartter syndrome: a new therapeutic approach].

The Bartter syndrome is a rare hereditary salt-wasting tubulopathy, characterized by metabolic alkalosis, hypokalemia, hyperreninemia and hyperaldosteronemia of varying severity. Indomethacin and high doses of oral potassium have been until now the therapeutic strategies used, with high risk of gastrointestinal injury. Since April 2009, aliskiren--renin inhibitor--has been used in individual cases of Bartter syndrome in adults, by ignoring its use in pediatrics.